The Company of Biologists

Table 3.

Cell proliferation

Age	n^{^*}	Body weight (gm)	Genotype	Osteoblasts (/0.01mm²)	% control	Pvalue^{^‡}	BrdU+ (/0.01mm²)	Labeling index (%)	% control	Pvalue^{^‡}
P7	5	4.2	Control^{^†}	31.9±2.2			7.9±1.3	24.7
	5	2.9	Fgfr2^cko	31.0±1.7	97	0.4	6.3±0.6	20.2	82	0.035
P15	4	8.7	Control^{^†}	22.8±3.3			5.6±0.6	24.4
	4	4.1	Fgfr2^cko	19.4±3.7	85	0.2	3.6±0.4	18.5	76	0.0014
P25	4	18.8	Control^{^†}	13.8±2.4			3.7±0.5	26.5
	4	9.7	Fgfr2^cko	14.7±1.3	106	0.6	2.0±0.3	13.4	50	0.0011

Age	n^{^*}	Body weight (gm)	Genotype	Osteoblasts (/0.01mm²)	% control	Pvalue^{^‡}	BrdU+ (/0.01mm²)	Labeling index (%)	% control	Pvalue^{^‡}
P7	5	4.2	Control^{^†}	31.9±2.2			7.9±1.3	24.7
	5	2.9	Fgfr2^cko	31.0±1.7	97	0.4	6.3±0.6	20.2	82	0.035
P15	4	8.7	Control^{^†}	22.8±3.3			5.6±0.6	24.4
	4	4.1	Fgfr2^cko	19.4±3.7	85	0.2	3.6±0.4	18.5	76	0.0014
P25	4	18.8	Control^{^†}	13.8±2.4			3.7±0.5	26.5
	4	9.7	Fgfr2^cko	14.7±1.3	106	0.6	2.0±0.3	13.4	50	0.0011

^*

Number of slides counted from one animal

Controls; P7 and P15, Fgfr2^+/flox;Dermo1^cre/+; P25, Fgfr2^+/flox;Dermo1^+/+

Two-tail P value from two-sample t-test assuming equal variances