... Metabolomics Cryoprotectant Compatible solute Preferential exclusion Protein aggregation Organisms as diverse as bacteria, plants and animals are known to naturally accumulate small protective molecules in response to various environmental stressors (recently reviewed in Yancey and Siebenaller...

... they protect from both global and focal ischemia in vivo and cell culture models of ischemia/reperfusion injury in vitr o, the mechanism of protection is not well understood. Protein aggregation is part of the etiology of chronic neurodegenerative diseases such as Huntington's and Alzheimer's, and recent data...