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Keywords: ouabain
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Journal Articles
J Exp Biol (2016) 219 (5): 626–630.
Published: 1 March 2016
...Kristin E. Spong; Tom R. Mazzetti; R. Meldrum Robertson ABSTRACT Spreading depression (SD) is associated with large changes in extracellular ion concentrations and can be induced by impairing mechanisms of K + ion homeostasis. We tested activity dependence of SD in the locust model of ouabain...
Journal Articles
J Exp Biol (2015) 218 (13): 2023–2029.
Published: 1 July 2015
... filled with buffered NaCl (154 mmol l −1 plus 1 mmol l −1 HEPES) and bathed in mosquito saline with theophylline, fluid absorption was augmented (50.0±5.8 nl min −1 , N =12, ±s.e.m.). Concanamycin A (10 µmol l −1 ), ouabain (1 mmol l −1 ), and acetazolamide (1 mmol l −1 ) affected V te in different ways...
Includes: Supplementary data
Journal Articles
J Exp Biol (2012) 215 (3): 497–507.
Published: 1 February 2012
... + /K + -ATPase inhibitor ouabain (10 mmol l –1 ; 21% reduction) and the vacuolar H + -ATPase inhibitor bafilomycin (5 μmol l –1 ; 21% reduction), and by the organic anions PAH (10 mmol l –1 ; 44% reduction) and probenecid (10 mmol l –1 ; 61% reduction, concentration-dependent inhibition). Transport...
Journal Articles
J Exp Biol (2009) 212 (3): 373–377.
Published: 1 February 2009
... in supplying acid–base equivalents to the respective transporters. Furthermore, any apical processes proposed to be involved in alkali secretion or acid absorption must be Cl – independent and insensitive to DIDS,amiloride, Zn 2+ and ouabain. These results argue against the involvement of putative apical Cl...
Journal Articles
J Exp Biol (2004) 207 (26): 4623–4631.
Published: 15 December 2004
... hemolymph-like salines. Although hemolymph-side ouabain did not affect this current, concanamycin significantly reduced I sc without altering preparation conductance, suggesting V-ATPase-driven Cl – absorption on the distal side of the posterior gill lamellae, as known to occur in diadromous crabs adapted...
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J Exp Biol (1997) 200 (13): 1913–1917.
Published: 1 July 1997
... with ouabain. The time to reach full depolarization ([K + ] o plateau) was three times longer in the anoxic brain than in normoxic controls, and the initial rate of K + leakage was reduced by approximately 70 %. Superfusing the brain before and during anoxia with the general adenosine receptor blocker...
Journal Articles
J Exp Biol (1995) 198 (12): 2575–2580.
Published: 1 December 1995
... been blocked by ouabain revealed no change in K + permeability in crucian carp brain in response to anoxia. Furthermore, superfusing the brain of anoxic crucian carp with the K ATP channel blocker glibenclamide did not alter the efflux rate of K + after glycolysis had been inhibited with IAA...
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J Exp Biol (1988) 137 (1): 265–276.
Published: 1 July 1988
...S. H. P. Maddrell; J. A. Overton ABSTRACT Ouabain, at all concentrations higher than 2×l0 −7 mol l −1 , stimulates the rate at which the Malpighian tubules of the insect, Rhodnius , transport sodium ions and fluid into the lumen. An effect on paracellular movement of sodium ions is unlikely because...
Journal Articles
J Exp Biol (1986) 121 (1): 43–54.
Published: 1 March 1986
... stops when sodium is replaced by choline in the perfusion fluid and is much reduced by treatment with ouabain, particularly when this is applied to the basolateral faces of the cells. These results suggest that ion absorption may be driven by an Na/K exchange pump. Cyclic AMP at 10 −2 moll −1 increases...