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Keywords: ouabain
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Journal Articles
J Exp Biol (2016) 219 (5): 626–630.
Published: 1 March 2016
...Kristin E. Spong; Tom R. Mazzetti; R. Meldrum Robertson ABSTRACT Spreading depression (SD) is associated with large changes in extracellular ion concentrations and can be induced by impairing mechanisms of K + ion homeostasis. We tested activity dependence of SD in the locust model of ouabain...
Journal Articles
J Exp Biol (2015) 218 (13): 2023–2029.
Published: 1 July 2015
... filled with buffered NaCl (154 mmol l −1 plus 1 mmol l −1 HEPES) and bathed in mosquito saline with theophylline, fluid absorption was augmented (50.0±5.8 nl min −1 , N =12, ±s.e.m.). Concanamycin A (10 µmol l −1 ), ouabain (1 mmol l −1 ), and acetazolamide (1 mmol l −1 ) affected V te in different ways...
Includes: Supplementary data
Journal Articles
J Exp Biol (2012) 215 (3): 497–507.
Published: 1 February 2012
... + /K + -ATPase inhibitor ouabain (10 mmol l –1 ; 21% reduction) and the vacuolar H + -ATPase inhibitor bafilomycin (5 μmol l –1 ; 21% reduction), and by the organic anions PAH (10 mmol l –1 ; 44% reduction) and probenecid (10 mmol l –1 ; 61% reduction, concentration-dependent inhibition). Transport...
Journal Articles
J Exp Biol (2009) 212 (3): 373–377.
Published: 1 February 2009
... in supplying acid–base equivalents to the respective transporters. Furthermore, any apical processes proposed to be involved in alkali secretion or acid absorption must be Cl – independent and insensitive to DIDS,amiloride, Zn 2+ and ouabain. These results argue against the involvement of putative apical Cl...
Journal Articles
J Exp Biol (2004) 207 (26): 4623–4631.
Published: 15 December 2004
... hemolymph-like salines. Although hemolymph-side ouabain did not affect this current, concanamycin significantly reduced I sc without altering preparation conductance, suggesting V-ATPase-driven Cl – absorption on the distal side of the posterior gill lamellae, as known to occur in diadromous crabs adapted...
Journal Articles
J Exp Biol (2002) 205 (7): 897–904.
Published: 1 April 2002
... depolarized by 11±3 mV and 16±3 mV, respectively( N =11; 11). This conductance could also be inhibited by Ba 2+ , which depolarized a V bl of -71±5 mV by 9±3 mV ( N =5). The pump inhibitor ouabain (1 mmol l -1 ) depolarized V bl , but addition of furosemide to bath solution did not affect V bl . The[K...
Journal Articles
J Exp Biol (2002) 205 (1): 71–77.
Published: 1 January 2002
... not differ significantly. Reducing the saline concentration of bath and perfusate from 30 ‰ to 20 ‰ or 10 ‰ increased significantly the TEPDs of these gills. TEPDs of gill 6 (representative of posterior gills) were reduced by 69±5 % and 60±5 % after perfusion with ouabain or BaCl 2 (5 mmol l –1 each...
Journal Articles
J Exp Biol (1990) 149 (1): 293–305.
Published: 1 March 1990
... concentration differences (internal perfusate=273 mmoll −1 ; external perfusate=l–80mmoll −1 ) and depended strongly on the concentration of sodium ions present in the external perfusate. The maximum rate of influx was 3.24μmolg −1 min −1 and the K m for this process was 23.0mmoll −1 . Ouabain added...
Journal Articles
J Exp Biol (1986) 121 (1): 43–54.
Published: 1 March 1986
... stops when sodium is replaced by choline in the perfusion fluid and is much reduced by treatment with ouabain, particularly when this is applied to the basolateral faces of the cells. These results suggest that ion absorption may be driven by an Na/K exchange pump. Cyclic AMP at 10 −2 moll −1 increases...