.... The molecular details reveal up to 14 protein subunits arranged in (i) a cytoplasmic V 1 complex, which mediates the hydrolysis of ATP, and (ii) a membrane-embedded V 0 complex, which translocates H + across the membrane. Clever experiments have revealed the V-type H + ATPase as a molecular motor akin to F-type...

...@mail.tju.edu 18 2 2003 © The Company of Biologists Limited 2003 2003 signal transduction protein kinase diffusion endocytosis molecular motor mitogen activated protein kinase (MAPK) traveling wave The deciphering of the genome of several organisms including humans has...