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Keywords: metabolic rate suppressionClose
J Exp Biol (2022) 225 (4): jeb196725.
Published: 21 February 2022
... hypoxic ventilatory response, robust metabolic rate suppression and decreased thermogenesis ( Mortola, 1999 ; Mortola et al., 1989 ). In most adult hypoxia-intolerant mammals, ventilatory and metabolic responses to hypoxia are regulated by excitatory glutamatergic signalling pathways ( Pamenter et al...
J Exp Biol (2019) 222 (22): jeb211243.
Published: 21 November 2019
... ; Pamenter et al., 2015 ). A key finding was that naked mole-rats can suppress their metabolism by up to 85% in acute hypoxia ( Pamenter et al., 2018 ). Marked metabolic rate suppression is very important in hypoxia, as it reduces ATP demand to match limited ATP supply ( Buck and Pamenter, 2006 ). Hypoxic...
J Exp Biol (2011) 214 (2): 191–199.
Published: 15 January 2011
... -independent ATP production. Thus, it is reasonable to speculate that the degree of metabolic rate suppression and the quantity of stored fermentable fuel is strongly selected for in hypoxia-tolerant fishes; however, these assertions have not been tested in a phylogenetic comparative model. jrichard...