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Keywords: lifespan
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Journal Articles
J Exp Biol jeb.243205.
Published: 16 May 2022
... of sex. Our main finding that old birds with higher glucose tolerance had better survival supports the hypothesis that the capacity to efficiently cope with a physiological challenge predicts lifespan, at least in old birds. * Authors for correspondence: bibianac.montoyal@uatx.mx ; s.verhulst...
Journal Articles
J Exp Biol (2021) 224 (9): jeb233734.
Published: 4 May 2021
... of an organism's phenotype is modified during aging (Kirkwood 2005); thus, lifespan is limited by the rate of an organism's aging. Various processes, including accumulation of oxidative damage, increases in inflammation, telomere shortening, mitochondrial dysfunction and misfolded proteins may affect the rate...
Journal Articles
J Exp Biol (2020) 223 (22): jeb226027.
Published: 23 November 2020
... and fitness is less clear. Here, we show that Drosophila exposed to hypoxia during their larval period subsequently show reduced starvation stress resistance and shorter lifespan as adults, with these effects being stronger in males. We find that these effects are associated with reduced whole-body insulin...
Journal Articles
J Exp Biol (2020) 223 (Suppl_1): jeb209296.
Published: 1 February 2020
...Michael Poeschla; Dario R. Valenzano; Michael H. Dickinson; Leslie B. Vosshall; Julian A. T. Dow ABSTRACT Lifespan is a remarkably diverse trait in nature, ranging from just hours in adult mayflies to hundreds of years in the Greenland shark and quahog clam. Great disparities in lifespan are often...
Journal Articles
J Exp Biol (2020) 223 (1): jeb212704.
Published: 2 January 2020
..., which generally include a reduction in fitness of the carrier of the driving allele, making such systems ‘selfish’. The t haplotype is one such driver, found in house mice. It is linked to a reduction in litter size in matings among heterozygous animals, but also to increased lifespan in wild females...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (21): jeb181115.
Published: 29 October 2018
..., with the nutritional optima being identified at P:C 1:4 for lifespan (P+C 120 g l −1 ), 1:2 for egg-to-adult viability (120 g l −1 ), 1:1 for female body mass at adult eclosion (240 g l −1 ) and lifetime fecundity (360 g l −1 ), 2:1 for larval developmental rate (60 g l −1 ) and 8:1 for egg production rate (120 g l −1...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (15): jeb181586.
Published: 10 August 2018
...Oscar Vedder; Simon Verhulst; Erica Zuidersma; Sandra Bouwhuis ABSTRACT High growth rate is associated with a short lifespan, but the physiological basis for this trade-off is not well known. Telomere length predicts individual lifespan and in this study we investigated whether embryonic growth...
Journal Articles
J Exp Biol (2018) 221 (14): jeb183228.
Published: 26 July 2018
...Joseph W. Margotta; Stephen P. Roberts; Michelle M. Elekonich ABSTRACT Frequent and highly aerobic behaviors likely contribute to naturally occurring stress, accelerate senescence and limit lifespan. To understand how the physiological and cellular mechanisms that determine the onset and duration...
Journal Articles
J Exp Biol (2018) 221 (9): jeb175554.
Published: 11 May 2018
... time, reproduction and lifespan of the organism. Studies so far have focused on discriminating between protein and carbohydrate uptake and the consequences on fitness components at different life stages. However, it is largely unknown whether and how the developmental diets, which may entail habitat...
Includes: Supplementary data
Journal Articles
J Exp Biol (2017) 220 (5): 900–907.
Published: 1 March 2017
.... WJL even leads to a lifespan extension in nutritionally challenged males. These results demonstrate that L.p. WJL is a beneficial partner for Drosophila melanogaster through its entire life cycle. Thus, commensal bacteria allow the earlier emergence and longer survival of fit and fertile individuals...
Includes: Supplementary data
Journal Articles
J Exp Biol (2016) 219 (6): 824–833.
Published: 15 March 2016
... no competing or financial interests. 10 12 2015 14 1 2016 © 2016. Published by The Company of Biologists Ltd 2016 Highlighted Article: More fat, live longer: positive association between fat content and lifespan in ants. Ants Flexibility Fat Lifespan Nutrition...
Includes: Supplementary data
Journal Articles
J Exp Biol (2014) 217 (4): 580–589.
Published: 15 February 2014
... stress and defense responses to exogenous stressors. In order to rigorously examine correlations between pre-adult development time and other life history traits, we assayed pre-adult survivorship, starvation and desiccation resistance, body size and body weight, fecundity and adult lifespan in faster...
Journal Articles
J Exp Biol (2010) 213 (20): 3441–3448.
Published: 15 October 2010
... invertebrate lifespan and induce aging-related physiological changes. However, the nature of the relationship between atmospheric oxygen, oxidative stress, and lifespan across a range of oxygen levels is poorly known. Developmental responses are likely to play a strong role, as prior research has shown strong...
Journal Articles
J Exp Biol (2009) 212 (23): 3810–3816.
Published: 1 December 2009
... of the forewing length (A) and lifespan (B) Source d.f. MS F P (A) Forewing length Species 3 18915 1935 0.000 Sex 1 27.864 2.851 0.094 Species × sex 3 22.754 2.328 0.077 Error 132 9.773 (B) Lifespan Species 3 1.014 51.916 0.000 Sex 1...
Journal Articles
J Exp Biol (2007) 210 (12): 2170–2180.
Published: 15 June 2007
...Hagai Rottenberg SUMMARY In animals, longevity (maximal lifespan) is inversely related to mass-specific basal metabolic rates. However, contrary to expectation, in several mammalian taxa, exceptional longevity is associated with high basal metabolic rate, and also fast evolution of mtDNA-coded...
Includes: Supplementary data
Journal Articles
J Exp Biol (2005) 208 (9): 1593–1599.
Published: 1 May 2005
... of membrane proteins. These differences in membrane composition may also represent a link between metabolism and aging. They probably explain the lifespan-body size relationship in mammals and birds and also the mammal-bird difference in lifespan. Over the last couple of decades, the relative contribution...
Journal Articles
J Exp Biol (2005) 208 (4): 697–705.
Published: 15 February 2005
...Yanmei Zhao; Hui Sun; Jun Lu; Xiaoxue Li; Xia Chen; Dan Tao; Weifeng Huang; Baiqu Huang SUMMARY The heat shock proteins (Hsps) play a positive role in lifespan determination, and histone acetylation has been shown to be involved in transcription of hsp genes in Drosophila . To further determine...