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Keywords: ion channel
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Journal Articles
J Exp Biol (2023) 226 (5): jeb245222.
Published: 10 March 2023
... and reproduction in any medium provided that the original work is properly attributed. Summary: Chronic estradiol replacement in ovariectomized mice influences voltage-gated potassium channel function. CRH Estradiol Ion channel Intrinsic excitability Ovariectomy M-type potassium channel A-type...
Journal Articles
Journal Articles
J Exp Biol (2017) 220 (3): 469–477.
Published: 1 February 2017
... is responsive to amino acid changes in disparate parts of the protein; changes in these different parts interact in complex ways. Allostery Cnidaria Ion channel Structure–function The voltage-gated potassium ion (Kv) channels are transmembrane protein tetramers, consisting of a pore domain (PD...
Includes: Supplementary data
Journal Articles
J Exp Biol (2015) 218 (4): 537–550.
Published: 15 February 2015
... by cellular anatomy; active components include ion channels specified by their selectivity and voltage dependence. A recurring theme is the role of inactivating potassium channels in regulating performance. Although different aspects of cnidarian behaviour are controlled by separate neuronal systems...
Journal Articles
J Exp Biol (2010) 213 (9): 1417–1424.
Published: 1 May 2010
... © 2010. 2010 invertebrates ion channel olfaction phosphoinositides sensory transduction Phosphoinositides (PIs) are well known to play important and complex roles in the regulation of ion-transporting proteins, ranging from the maintenance of the structural integrity of signaling...
Journal Articles
J Exp Biol (2009) 212 (13): 1973–1979.
Published: 1 July 2009
... that this similarity extended to the ORs, which were originally annotated as GPCRs. Surprisingly,recent evidence shows that insect ORs can act like ligand-gated ion channels,either completely or partially bypassing the amplification steps connected to the activation of G proteins. Although the involvement of G...
Journal Articles
Journal Articles
J Exp Biol (2008) 211 (11): 1792–1804.
Published: 1 June 2008
.... A substantial proportion of neuronal energy consumption is related to the movements of ions across the neuronal cell membrane through ion channels, though other processes such as vesicle loading and transmitter recycling also consume energy. Many of the energetic costs within neurons are linked to 3Na + /2K...
Journal Articles
J Exp Biol (2005) 208 (16): 3055–3063.
Published: 15 August 2005
..., of sodium and potassium currents of somatic muscle of larval Danio rerio to investigate their possible contribution to once-only firing. Our computer model incorporated simulated sodium and potassium ion channels based on steady-state and kinetic parameters derived from a recent electrophysiological study...
Journal Articles
Journal Articles
J Exp Biol (1999) 202 (14): 1939–1951.
Published: 15 July 1999
... visual system central nervous system insect electrophysiology ion channel K + current Ca 2+ current locust Schistocerca gregaria In insects, the perception and processing of visual information has been widely studied in numerous preparations. The sensory input provided...
Journal Articles
Journal Articles
J Exp Biol (1997) 200 (18): 2377–2386.
Published: 1 September 1997
..., the channel responded to FMRFamide. Taken together, these data provide the first evidence for a peptide-gated ion channel. Comparison of the properties of the expressed FaNaCh with the native neuronal channel show small differences in the sensitivities to some drugs and in channel conductance. It is not yet...
Journal Articles
J Exp Biol (1993) 182 (1): 113–130.
Published: 1 September 1993
...Mary Kate Worden; Rami Rahamimoff; Edward A. Kravitz ABSTRACT Ion channel activity in the sarcolemmal membrane of muscle fibers is critical for regulating the excitability, and therefore the contractility, of muscle. To begin the characterization of the biophysical properties of the sarcolemmal...
Journal Articles
Journal Articles
J Exp Biol (1988) 138 (1): 499–515.
Published: 1 September 1988
...K. S. Kits; P. N. R. Usherwood ABSTRACT The ion-selectivity of the extrajunctional glutamate-gated ion channel in locust extensor tibiae muscle was studied using the patch-clamp technique. The alkali metal ions Li + , Na + , K + , Rb + and Cs + were all highly permeant, with reversal potentials...
Journal Articles
J Exp Biol (1987) 127 (1): 191–209.
Published: 1 January 1987
... is an interburst closed state. * To whom reprint requests should be sent. 15 09 1986 © 1987 The Company of Biologists Ltd. 1987 ion channel stretch activation K + channel Lymnaea stagnalis To determine the number of kinetically distinguishable states which the SAK...
Journal Articles
J Exp Biol (1986) 124 (1): 287–306.
Published: 1 September 1986
... neurone growth cones. This provides the first direct evidence that channel modulation occurs in nerve processes and increases the likelihood of channel modulation at the nerve terminal. modulation ion channel cyclic AMP © 1986 by Company of Biologists 1986 Neurotransmitter actions can...
Journal Articles
J Exp Biol (1985) 117 (1): 215–235.
Published: 1 July 1985
... mechanoreceptor voltage dependence ion channel protozoan Following the work of Jenkinson (1960) , (+)-tubocurarine (TC) has been regarded as a ‘competitive antagonist’ of acetylcholine at the vertebrate neuromuscular junction. However, the reports of Manalis (1977) , Katz & Miledi (1978...