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Keywords: genomics
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Journal Articles
J Exp Biol (2020) 223 (24): jeb191262.
Published: 17 December 2020
.... Transcriptomics Metabolomics Genomics RNA-seq Hypothesis testing A goal of comparative physiology is to understand the diverse mechanisms that allow animals to function and survive in their environments. Comparative physiologists (1) inquire vertically across levels of biological organization, (2...
Journal Articles
J Exp Biol (2019) 222 (Suppl_1): jeb191890.
Published: 6 February 2019
..., suggesting an epigenetic control of their migration. The genes and epigenetic changes underpinning migratory behaviour remain largely unknown. The revolution in (epi)genomics and functional genomic tools holds great promise to rapidly move the field of migration genetics forward. Here, we review our current...
Journal Articles
J Exp Biol (2018) 221 (8): jeb176917.
Published: 25 April 2018
... in aggression in the honey bee. Behavioral plasticity Genomics Neural energetics Alzheimer's disease Traumatic brain injury Energy metabolism is so fundamental to neuronal signaling that metabolic dysfunction underlies most diseases associated with cognitive impairment, including Alzheimer's...
Includes: Supplementary data
Journal Articles
J Exp Biol (2018) 221 (5): jeb170670.
Published: 12 March 2018
... . Cell Metab.   13 , 125 - 137 . 10.1016/j.cmet.2011.01.006 Aubin-Horth , N. and Renn , S. C. P. ( 2009 ). Genomic reaction norms: using integrative biology to understand molecular mechanisms of phenotypic plasticity . Mol. Ecol.   18 , 3763 - 3780 . 10.1111/j.1365-294X.2009.04313...
Includes: Supplementary data
Journal Articles
J Exp Biol (2015) 218 (1): 114–122.
Published: 1 January 2015
... at a molecular level; however, recent progress on sequencing technology and genome editing tools have begun to blur the lines between model and non-model organisms, opening numerous new avenues for investigation. Here, I review examples of epigenetic phenomena in non-model organisms that have emerged...
Journal Articles
J Exp Biol (2013) 216 (18): 3474–3482.
Published: 15 September 2013
... the paper. COMPETING INTERESTS No competing interests declared. 24 2 2013 17 5 2013 © 2013. Published by The Company of Biologists Ltd 2013 genomics microarrays social evolution nest initiation A common feature of animal societies is social regulation, where...
Includes: Supplementary data
Journal Articles
J Exp Biol (2011) 214 (10): 1773–1782.
Published: 15 May 2011
... is monitoring for changes in their phototactic behavior. In most arthropods, histamine has been shown to play a key role in the visual system. Currently, nothing is known about histaminergic signaling in either D. magna or D. pulex . Here, a combination of immunohistochemistry and genome mining was used...
Journal Articles
J Exp Biol (2008) 211 (22): 3636–3649.
Published: 15 November 2008
...-induced transcription factor responsible for the rapid synthesis of heat shock proteins ( Voellmy, 2004 ). * Author for correspondence (e-mail: tevans@stanford.edu ) 18 9 2008 © The Company of Biologists Limited 2008 2008 fish genomics Gillichthys mirabilis microarray...
Includes: Supplementary data
Journal Articles
J Exp Biol (2007) 210 (11): 1847–1857.
Published: 1 June 2007
... to combining genomic and physiological studies, one must bear in mind that the massive datasets associated with genomic studies need to be further enlarged to enable estimates of individual variation. It is also important to remember that microarray and proteomic data give the levels of mRNA and proteins...
Journal Articles
J Exp Biol (2007) 210 (9): 1497–1506.
Published: 1 May 2007
...Piero Carninci SUMMARY The principal route to understanding the biological significance of the genome sequence comes from discovery and characterization of that portion of the genome that is transcribed into RNA products. We now know that this`transcriptome' is unexpectedly complex and its precise...
Includes: Supplementary data
Journal Articles
J Exp Biol (2007) 210 (9): 1607–1612.
Published: 1 May 2007
...Stuart K. Kim SUMMARY Development of functional genomics tools has made it possible to define the aging process by performing genome-wide scans for transcriptional differences between the young and the old. Global screens for age regulation have been performed for worms and flies, as well as many...
Includes: Supplementary data
Journal Articles
J Exp Biol (2007) 210 (9): 1622–1631.
Published: 1 May 2007
... multi-component systems. Systems biology has emerged in the post-genome era as the successor to reductionism. In my opinion, systems biology and physiology are synonymous. Both disciplines seek to understand multi-component processes or `systems' and the underlying pathways of information flow from...
Includes: Supplementary data
Journal Articles
J Exp Biol (2006) 209 (14): 2660–2677.
Published: 15 July 2006
... Environmental Biology, University of Southern California, 3616 Trousdale Parkway, #107, Mail Code 0371 Los Angeles, CA 90089, USA 24 4 2006 © The Company of Biologists Limited 2006 2006 genomics transcriptome stress fish heat shock goby Gillichthys mirabilis The coordinated...
Includes: Supplementary data
Journal Articles
J Exp Biol (2004) 207 (15): 2551–2563.
Published: 1 July 2004
... (transmission blocking vaccines), genetic manipulation or chemical incapacitation of the vector. During the past decade, mosquito research has been energized by several breakthroughs, including the successful transformation of anopheline vectors, analysis of gene function by RNAi,genome-wide expression...
Journal Articles
J Exp Biol (2003) 206 (21): 3789–3802.
Published: 1 November 2003
...D. L. Doolan; J. C. Aguiar; W. R. Weiss; A. Sette; P. L. Felgner; D. P. Regis; P. Quinones-Casas; J. R. Yates, III; P. L. Blair; T. L. Richie; S. L. Hoffman; D. J. Carucci SUMMARY Recent advances in the fields of genomics, proteomics and molecular immunology offer tremendous opportunities...
Journal Articles
J Exp Biol (2002) 205 (16): 2429–2451.
Published: 15 August 2002
... from Plasmodium spp. genome, could be an essential tool for understanding the molecular basis of malaria. We are grateful to Drs Robert W. Gwadz, Thomas J. Kindt and Louis H. Miller for encouragement and support. We also thank Brenda Rae Marshall for editorial support. References...