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Keywords: epigenetics
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Journal Articles
J Exp Biol (2023) 226 (19): jeb245851.
Published: 29 September 2023
... highlight research that uses NCEs in predator–prey systems to provide novel insights into cognition, adaptation, epigenetic inheritance and aging. I discuss the evolution of instinct, anxiety and other cognitive disorders, the shaping of brain connectomes, stress-induced aging and the development...
Journal Articles
J Exp Biol (2023) 226 (13): jeb245475.
Published: 10 July 2023
... at CpG dinucleotides and, typically, high DNA methylation decreases gene expression, particularly when it occurs in promoters. The CpG content of gene regulatory regions may therefore represent one form of epigenetic potential (EP), a genomic means to enable gene expression and hence adaptive phenotypic...
Includes: Supplementary data
Journal Articles
Journal Articles
J Exp Biol (2022) 225 (Suppl_1): jeb243264.
Published: 8 March 2022
... in animals. Cellular stress response DNA damage Epigenetics Chromoanagenesis Transposable elements National Science Foundation http://dx.doi.org/10.13039/100000001 MCB-2127516 All living organisms exist under the stress of their environment. Stress, in this sense, refers...
Journal Articles
J Exp Biol (2022) 225 (Suppl_1): jeb243411.
Published: 8 March 2022
... of data and analytic methods. Previous studies have linked physiological features to coding DNA sequence, regulatory DNA sequence, and epigenetic state, but few have disentangled their relative contributions or unambiguously distinguished causative effects (‘drivers’) from correlations. Progress has been...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (Suppl_1): jeb239319.
Published: 24 February 2021
... of these mechanisms and continuum, I also present how the interplay of the microbiome, epigenetics and parental effects creates additional avenues for rapid acclimatization. To consider under what conditions epigenetic inheritance has a more substantial role, I propose investigation into the offset of timing...
Journal Articles
Journal Articles
J Exp Biol (2020) 223 (13): jeb220632.
Published: 3 July 2020
...Cheryl Walker; Warren Burggren ABSTRACT The epigenome determines heritable patterns of gene expression in the absence of changes in DNA sequence. The result is programming of different cellular-, tissue- and organ-specific phenotypes from a single organismic genome. Epigenetic marks that comprise...
Journal Articles
Journal Articles
Journal Articles
J Exp Biol (2019) 222 (15): jeb203620.
Published: 5 August 2019
... by histone modifications such as histone acetylation. Here, we investigated a group of key epigenetic modifiers, histone deacetylases (HDAC), which are known to play an important role in many biological processes such as development, healing and regeneration. Through our transcriptome data, we identified...
Includes: Supplementary data
Journal Articles
Journal Articles
J Exp Biol (2018) 221 (23): jeb153163.
Published: 26 November 2018
... of acceptance of genetic accommodation in some cases is related to a lack of information on its molecular mechanisms. However, recent reports of epigenetic transgenerational inheritance now provide a plausible mechanism through which genetic accommodation may act, and we review this research here. We also...
Journal Articles
J Exp Biol (2017) 220 (23): 4330–4338.
Published: 1 December 2017
... . 10.1186/gb-2005-6-4-r36 Heijmans , B. , Tobi , E. W. , Stein , A. D. , Putter , H. , Blauw , G. L. , Susser , E. S. , Slagboom , P. E. and Lumey , L. H. ( 2008 ). Persistent epigenetic differences associated with prenatal exposure to famine in humans . Proc. Natl...
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Journal Articles
J Exp Biol (2017) 220 (19): 3579–3587.
Published: 1 October 2017
...-related hormones. A big challenge, however, is in determining the history of exposure of an organism to stress, because the release of stress hormones can show an acute (and recent) but not a sustained exposure to stress. Epigenetic tools provide an alternative option to evaluate past exposure to long...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Exp Biol (2015) 218 (1): 32–40.
Published: 1 January 2015
...Per Jensen; Hans H. Hoppeler In this review, it is argued that greatly improved understanding of domestication may be gained from extending the field of behaviour genetics to also include epigenetics. Domestication offers an interesting framework of rapid evolutionary changes caused by well-defined...
Journal Articles
J Exp Biol (2015) 218 (1): 7–13.
Published: 1 January 2015
...Denis Noble; Hans H. Hoppeler Experimental results in epigenetics and related fields of biological research show that the Modern Synthesis (neo-Darwinist) theory of evolution requires either extension or replacement. This article examines the conceptual framework of neo-Darwinism, including...
Includes: Supplementary data