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J Exp Biol (2004) 207 (10): 1625–1632.
Published: 15 April 2004
... electron microscopic studies. Generally receptor sequestration follows its desensitization, which is initiated by receptor phosphorylation by G-protein-coupled receptor kinase. We cloned and sequenced the gene fragment of 407 nucleotides homologous to theβ-adrenergic receptor kinase (βARK): its deduced...
J Exp Biol (2004) 207 (3): 411–416.
Published: 22 January 2004
... role in venom production. This receptor had relatively low sensitivity to noradrenaline (pD 2 =4.77±0.09, N =7)and to phenylephrine (pD 2 =3.77±0.06, N =11). The receptor became desensitized just after venom extraction (pD 2 to phenylephrine fell to 3.27±0.02, N =6) and the sensitivity remained low...
J Exp Biol (2003) 206 (3): 627–636.
Published: 1 February 2003
... desensitization. Either this represents a unique new class of ATP receptors,in which PPNDS is an agonist instead of an antagonist, or PPNDS (and other drugs like it) may actually be an agonist in many other cell types in which prolonged exposure is necessary for inhibition. * Author for correspondence (e...