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Keywords: colchicine
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Journal Articles

Microtubule-dependent relocation of branchial V-H + -ATPase to the basolateral membrane in the Pacific spiny dogfish ( Squalus acanthias ): a role in base secretion

Martin Tresguerres, Scott K. Parks, Fumi Katoh, Greg G. Goss
Journal: Journal of Experimental Biology
J Exp Biol (2006) 209 (4): 599–609.
DOI: https://doi.org/10.1242/jeb.02059
Published: 15 February 2006
... dogfish. To further investigate this putative base-secretive process we performed similar experiments with the addition of colchicine, an inhibitor of cytoskeleton-dependent cellular trafficking processes. Blood pH and plasma total CO 2 were significantly higher in the colchicines-treated,HCO 3 - -infused...
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Journal Articles

Active ammonia excretion across the gills of the green shore crab Carcinus maenas : participation of Na + /K + -ATPase, V-type H + -ATPase and functional microtubules

Dirk Weihrauch, Andreas Ziegler, Dietrich Siebers, David W. Towle
Journal: Journal of Experimental Biology
J Exp Biol (2002) 205 (18): 2765–2775.
DOI: https://doi.org/10.1242/jeb.205.18.2765
Published: 15 September 2002
.... In the euryhaline green shore crab Carcinus maenas , active excretion of ammonia across isolated gills is reduced by inhibitors of the Na + /K + -ATPase and vacuolar-type H + -ATPase. In addition, a functional dynamic microtubule network is necessary, since application of colchicine, taxol or thiabendazole leads...
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