...Andrew B. Barron; Ryszard Maleszka; Paul G. Helliwell; Gene E. Robinson SUMMARY The role of cocaine as an addictive drug of abuse in human society is hard to reconcile with its ecological role as a natural insecticide and plant-protective compound, preventing herbivory of coca plants( Erythroxylum...

...Kathleen Carter; Ken Lukowiak; James O. Schenk; Barbara A. Sorg SUMMARY The persistence of drug addiction suggests that drugs of abuse enhance learning and/or impair extinction of the drug memory. We studied the effects of repeated cocaine on learning, memory and reinstatement in the pond snail...

...Aurelio Galli; Louis J. Defelice; Billie-Jeanne Duke; Kimberly R. Moore; Randy D. Blakely ABSTRACT Transport of norepinephrine (NE + ) by cocaine- and antidepressant-sensitive transporters in presynaptic terminals is predicted to involve the cotransport of Na + and Cl - , resulting in a net...

..., Addiction Research Center, Box 5180, Baltimore, MA 21224, USA. ©The Company of Biologists Limited 1994 cocaine Parkinson’s disease symporters antiporters Neurons and glial cells use transporter molecules that are products of at least three distinct gene families to aid in temporal...

...Randy D. Blakely; Louis J. De Felice; H. Criss Hartzell ABSTRACT Cocaine- and antidepressant-sensitive norepinephrine and serotonin transporters (NETs and SERTs) are closely related members of the Na+/Cl − transporter gene family, whose other members include transporters for inhibitory amino acid...