... The authors declare no competing financial interests. 24 3 2014 24 6 2014 © 2014. Published by The Company of Biologists Ltd 2014 Reactive oxidative species Pyramidal neurons Whole-cell patch-clamp Anoxia tolerance Channel arrest Calcium Fluorescence Aerobic organisms...

.... 17 6 2013 21 8 2013 © 2013. Published by The Company of Biologists Ltd 2013 mitochondrial membrane potential mitochondrial BK channel pyramidal neurons whole-cell patch-clamp anoxia tolerance channel arrest The N -methyl- d -aspartate receptor (NMDAR...

.... * Author for correspondence (e-mail: buckl@zoo.utoronto.ca ) 15 9 2008 © The Company of Biologists Limited 2008 2008 anoxic depolarization channel arrest excitotoxic cell death Mammalian neurons are acutely sensitive to anoxia and rapidly undergo excitotoxic cell death (ECD...

... than of enhanced protective mechanisms. *Author for correspondence (e-mail: lutz@fau.edu ) 18 7 2001 © The Company of Biologists Limited 2001 2001 brain anoxia adenosine ATP frog Rana pipiens channel arrest depolarization. There is a vast literature...

... vertebrates, neonates and diving mammals, hypoxia-induced membrane destabilisation of the kind seen in adult mammals is either slow to develop or does not occur at all as a result of adaptive decreases in membrane permeability (i.e. ion ‘channel arrest’) that dramatically reduce the energetic costs of ion...