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Keywords: amphibian heartClose
J Exp Biol (2007) 210 (3): 438–446.
Published: 1 February 2007
..., we examined the combined impact of CuCl 2 and hyperthermia (42°C) in the amphibian heart. Our results confirmed that thermal stress activates p38-MAPK in the frog heart and that its combination with CuCl 2 has an additive effect on the kinase phosphorylation ( Fig. 5 ), a result that agrees...
J Exp Biol (2006) 209 (7): 1344–1354.
Published: 1 April 2006
...Konstantina Stathopoulou; Catherine Gaitanaki; Isidoros Beis SUMMARY We investigated the activation of the p38-MAPK signalling pathway during extracellular pH changes in the isolated perfused amphibian heart. Extracellular alkalosis (pH 8.5 or 9.5) maximally activated p38-MAPK within 2 min (4.17...
J Exp Biol (2003) 206 (16): 2759–2769.
Published: 15 August 2003
...Catherine Gaitanaki; Stathopoulou Konstantina; Stavridou Chrysa; Isidoros Beis SUMMARY We investigated the activation of three subfamilies of MAPKs (ERK, JNKs and p38-MAPK) by oxidative stress in the isolated perfused amphibian heart. Activation of p43-ERK by 100 μmol l -1 H 2 O 2 was maximally...
J Exp Biol (2002) 205 (16): 2387–2397.
Published: 15 August 2002
...-stimulated hearts, a reaction completely blocked by the respective specific antagonists, or the specific p38-MAPK inhibitor SB203580. These findings indicate a functional correlation between p38-MAPK activation and ANP accumulation in the perfused amphibian heart. * Author for correspondence (e-mail...
J Exp Biol (2002) 205 (4): 443–454.
Published: 15 February 2002
... natriuretic peptide immunolocalisation amphibian heart Rana ridibunda . In physiologically stressful situations, survival of vertebrates is dependent upon uninterrupted heart function. Cardiac muscle is therefore particularly interesting because of its ability to maintain pump performance even...