... to 12‰ saltwater for 5 weeks to determine the effects of chronic exposure to saline environments. Following 5 weeks, plasma levels of hormones [e.g. progesterone, testosterone, estradiol, corticosterone, aldosterone (ALDO), angiotensin II (ANG II)] were quantified using liquid chromatography and tandem...

...), and cortisol treatment significantly increased transepithelial resistance (TER) and decreased paracellular [ 3 H]PEG-4000 flux. Epithelial permeability was unaffected by deoxycorticosterone or aldosterone. The GR antagonist RU486 as well as MR antagonists spironolactone and RU26752 significantly reduced...

... of metyrapone, blocking cortisol receptors through exposure to either RU-486 (GR antagonist) and spironolactone (MR antagonist), or through exogenous infusion of the tetrapod mineralocorticoid aldosterone (tetrapod MR agonist). The data demonstrate that lowering the activity of cortisol, either by inhibiting...

... and aldosterone over 30 min,while plasma renin activity (PRA) was decreased for a 120 min period. The plasma urea:creatinine ratio was elevated following infusion of VP. Urine output and osmotic clearance were increased by 69±18% (mean ± s.e.m. ) and 36±10%, respectively, but free water clearance and glomerular...

... and dietary salt may help maintain electrolyte homeostasis. Unlike most other aquatic mammals, sea otters commonly drink sea water and manatees frequently drink fresh water. Among the various taxonomic groups of marine mammals, the sensitivity of the renin–angiotensin–aldosterone system appears...

...Makoto Takada; Hideko Yai; Shinji Komazaki; Kazue Takayama-Arita ABSTRACT EDTA-treated larval bullfrog skin, in which apical and skein cells had been removed and only basal cells remained, was cultured in one of four media. These contained either aldosterone (Aldo) or a mixture of Aldo...

... from acutely or chronically aldosterone-treated lizards exhibited a considerably higher short-circuit current, potential difference and net Na + absorption than did untreated colons. Net Cl − transport was unaltered by acute treatment, but was totally abolished after chronic treatment. BaCl 2 rapidly...

...David L. Goldstein ABSTRACT House sparrows ( Passer domesticus ) had plasma aldosterone concentrations of about 180pgml −1 while maintained on a low-sodium diet (LS, 0.1mequiv Na + ingested per day), 135pgml −1 on a sodium intake of 0.9mequivday −1 (high-salt diet, HS) and 45pgml −1 on a Na...

... patch-clamp recordings of membrane capacitance and current fluctuations from MR cells demonstrate that a respiratory acid load and aldosterone produce rapid exocytotic insertion of DCCD-sensitive conductive membrane. A secondary role of the H + pump is to energize sodium absorption (JNa ) via principal...

... in aldosterone concentration during hypercapnia and a possible accompanying increase in corticosterone. The results suggest that the compensatory response to hypercapnia in larval A. tigrinum involves alterations in cutaneous ion transport which increase the extracellular SID. These cutaneous responses may...