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Keywords: Signal transductionClose
Merid N. Getahun, Michael Thoma, Sofia Lavista-Llanos, Ian Keesey, Richard A. Fandino, Markus Knaden, Dieter Wicher, Shannon B. Olsson, Bill S. Hansson
J Exp Biol (2016) 219 (21): 3428–3438.
Published: 1 November 2016
...) are found across protostomes, insect odorant receptors (ORs) have only been identified in winged insects. We therefore hypothesized that the unique signal transduction of ORs offers an advantage for odour localization in flight. Using Drosophila , we found expression and increased activity...
Includes: Supplementary data
J Exp Biol (2016) 219 (3): 445–456.
Published: 1 February 2016
... signal transduction mechanisms to respond with effective prey capture and predator evasion behaviors. However, the sensory biology of alveolate grazers is poorly understood. Using novel techniques that combine electrophysiological measurements and high-speed videomicroscopy, we investigated the sensory...
Includes: Supplementary data
J Exp Biol (2013) 216 (2): 208–217.
Published: 15 January 2013
.... * These authors contributed equally to this work † Author for correspondence ( email@example.com ) 2 8 2012 24 9 2012 © 2013. 2013 insulin insulin-like growth factor mosquito aging signal transduction A control and two treatment groups of A. stephensi females ( N...
J Exp Biol (2012) 215 (21): 3813–3822.
Published: 1 November 2012
... the reception of exogenous signals and subsequent endogenous signal transduction. To investigate the involvement of nitric oxide (NO) and cyclic GMP (cGMP) during larval settlement of B. amphitrite , we examined the effects of an NO donor and an NO scavenger, two nitric oxide synthase (NOS) inhibitors...
Includes: Supplementary data
J Exp Biol (2011) 214 (24): 4217–4222.
Published: 15 December 2011
... phagocytes by acting through κ-opioid receptors that are coupled with the AC–cAMP–PKA signal transduction mechanism. * Author for correspondence ( firstname.lastname@example.org ) 19 9 2011 © 2011. 2011 dynorphin phagocytosis opioid receptor signal transduction Dynorphins...
Mark Donowitz, Sachin Mohan, Cindy Xinjun Zhu, Tian-E Chen, Rong Lin, Boyoung Cha, Nicholas C. Zachos, Rakhilya Murtazina, Rafiquel Sarker, Xuhang Li
J Exp Biol (2009) 212 (11): 1638–1646.
Published: 1 June 2009
... to a small, putative α-helical domain of NHE3, between amino acids 586 and 605. The proteins which associate with NHE3 in this domain both stimulate and inhibit NHE3 activity. The interactions of many of these proteins are dynamic,often changing with signal transduction that affects NHE3 activity. Because...
J Exp Biol (2007) 210 (18): 3295–3300.
Published: 15 September 2007
... cold stress diapause signal transduction MAP kinase phosphorylation In addition to the cold hardening mechanisms exploited by overwintering insects that are in diapause, most insects have the capacity to quickly enhance their cold tolerance at other times of the year utilizing a mechanism...
J Exp Biol (2007) 210 (10): 1700–1714.
Published: 15 May 2007
... in the hypometabolic state. * Author for correspondence (e-mail: email@example.com ) 15 1 2007 © The Company of Biologists Limited 2007 2007 metabolic rate depression anoxia tolerance hibernation reversible protein phosphorylation signal transduction stress-induced gene...
J Exp Biol (2007) 210 (3): 438–446.
Published: 1 February 2007
... amphibian heart Rana ridibunda signal transduction Mammalian cardiac muscle is an obligate aerobic organ and under anaerobic conditions cannot produce enough energy to maintain essential cellular processes; thus, a constant supply of oxygen is indispensable for sustaining cardiac function...
J Exp Biol (2006) 209 (7): 1344–1354.
Published: 1 April 2006
... HSP27 amphibian heart Rana ridibunda signal transduction cellular signalling Intracellular pH is a very important physiological parameter since it affects proper protein folding and, therefore, enzyme activity and cellular processes, such as protein synthesis ( Roos and Boron, 1981...
J Exp Biol (2004) 207 (10): 1665–1674.
Published: 15 April 2004
... in combination with cadmium showed a synergistic effect on pHi and PK. These responses seem to be blocked by propranolol, metoprolol and prazosin. Our findings suggest a hormone-like effect of cadmium on digestive gland cells. The signal transduction pathway induced by cadmium involves the stimulation of PK, PKC...
J Exp Biol (2003) 206 (16): 2759–2769.
Published: 15 August 2003
... heart. Stimulation of p38-MAPK and the consequent phosphorylation of HSP27 may be important in cardioprotection under such conditions. MAPKs are key participants in signal transduction pathways activated by mitogenic stimuli, environmental stress and inflammatory agents. In mammals,the stress...
J Exp Biol (2003) 206 (12): 2073–2082.
Published: 15 June 2003
... to be responsible for enhanced signal transduction. Instead we demonstrate that the function of membrane localization is to increase the number (or average lifetime) of complexes between signaling partners. A hallmark of signaling pathways is the spatial separation of activation and deactivation mechanisms; e.g...
J Exp Biol (2003) 206 (7): 1107–1115.
Published: 1 April 2003
... major roles in the regulation of intracellular metabolism and gene expression and integral actions in many areas including growth and development, disease, apoptosis and cellular responses to external stresses. To date, this cellular signal transduction network has received relatively little attention...
J Exp Biol (2003) 206 (5): 827–832.
Published: 1 March 2003
...Kennedy S. Wekesa; Stephanie Miller; Audrey Napier SUMMARY Social behaviors of most mammals are profoundly affected by pheromones. Pheromones are detected by G-protein coupled receptors in the vomeronasal organ (VNO). To investigate the role of Gα q/11 in vomeronasal signal transduction pathways...
J Exp Biol (2001) 204 (17): 2975–2985.
Published: 1 September 2001
... complexes, the high level of 14-3-3.a expression in gill epithelium of the euryhaline teleost F. heteroclitus suggests that it is crucial for signal transduction in gill epithelial cells. We provide evidence that 14-3-3.a is involved in osmosensory signal transduction by showing that its mRNA and protein...
J Exp Biol (2001) 204 (16): 2899–2910.
Published: 15 August 2001
... Paramecium tetraurelia GPI anchor signal transduction folate There is a growing awareness that many surface membrane proteins are peripheral proteins, tethered to the membrane by a glycophosphatidylinositol(GPI) anchor (Lisanti et al.,1990 ; Cross,1990 ). These surface proteins serve many diverse...