... organisms. As an example, here we describe some key considerations in deriving and utilizing induced pluripotent stem cells from a hibernator. Stem cells Hibernation Torpor Physiological dormancy Reprogramming Adaptation Tau hyperphosphorylation Glossary Direct reprogramming...

... et al., 2011 ; Li et al., 2011 ; Moran-Crusio et al., 2011 ; Quivoron et al., 2011 ). Homozygous deletion of Tet3 is neonatal lethal while conditional deletion of maternal Tet3 impairs paternal genome reprogramming and causes developmental failure of the embryo ( Gu et al., 2011 ). Most...