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Keywords: Na+/K+/2Cl- cotransporter
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Journal Articles
J Exp Biol (2008) 211 (16): 2584–2599.
Published: 15 August 2008
...Junya Hiroi; Shigeki Yasumasu; Stephen D. McCormick; Pung-Pung Hwang; Toyoji Kaneko SUMMARY Cation–chloride cotransporters, such as the Na + /K + /2Clcotransporter (NKCC) and Na + /Cl – cotransporter (NCC), are localized to the apical or basolateral plasma membranes of epithelial cells...
Journal Articles
J Exp Biol (2007) 210 (6): 1015–1024.
Published: 15 March 2007
...Junya Hiroi; Stephen D. McCormick SUMMARY We compared seawater tolerance, gill Na + /K + -ATPase and Na + /K + /2Clcotransporter (NKCC)abundance, and mitochondria-rich cell (MRC) morphology of three salmonids,lake trout Salvelinus namaycush , brook trout Salvelinus fontinalis and Atlantic salmon...
Journal Articles
J Exp Biol (2006) 209 (24): 4908–4922.
Published: 15 December 2006
...Catherine Lorin-Nebel; Viviane Boulo; Charlotte Bodinier; Guy Charmantier SUMMARY This study combines a cellular and molecular analysis of the Na + /K + /2Cl - cotransporter (NKCC) to determine the osmoregulatory role of this protein in different tissues during the ontogeny of the sea bass. We have...
Journal Articles
J Exp Biol (2005) 208 (19): 3627–3636.
Published: 1 October 2005
... under all conditions. By contrast, the expression of Na + /K + -ATPaseα-subunit mRNA and Na + /K + /2Cl - cotransporter mRNA was strongly responsive to external salinity. During acclimation to dilute seawater, cotransporter mRNA increased 10-20-fold in posterior gills within the first 24 h while Na + /K...
Journal Articles
J Exp Biol (2005) 208 (11): 2023–2036.
Published: 1 June 2005
... of salinity on the localization of Na + /K + -ATPase,Na + /K + /2Cl - cotransporter (NKCC) and CFTR anion channel in chloride cells of the Hawaiian goby ( Stenogobius hawaiiensis ). J. Exp. Biol. 206 , 4575 -4583. Nielsen, S., Maunsbach, A. B., Ecelbarger, C. A. and Knepper, M. A. ( 1998...
Journal Articles
J Exp Biol (2004) 207 (21): 3707–3716.
Published: 1 October 2004
... and electrophysiological studies indicate that a bumetanide-sensitive Na + /K + /2Clcotransporter is the primary route for basolateral ion entry into the cell during fluid secretion. The goal of this study was to resolve the apparent conflict between relatively high secretion rates by tubules bathed in K + -free saline...
Journal Articles
J Exp Biol (2003) 206 (24): 4575–4583.
Published: 15 December 2003
...Stephen D. McCormick; Kristina Sundell; Björn Thrandur Björnsson; Christopher L. Brown; Junya Hiroi SUMMARY Na + /K + -ATPase,Na + /K + /2Cl - cotransporter (NKCC) and cystic fibrosis transmembrane conductance regulator (CFTR) are the three major transport proteins thought to be involved...
Journal Articles
J Exp Biol (2003) 206 (6): 949–957.
Published: 15 March 2003
... of the putative electroneutral Na + /K + /2Cl - cotransporter by 10 μmol l -1 bumetanide reversibly decreased fluid secretion rates, with no detectable change in membrane potentials. Ouabain (1 mmol l -1 ), an Na + /K + -ATPase inhibitor, irreversibly decreased fluid secretion rates but had no effect...
Journal Articles
J Exp Biol (2002) 205 (6): 745–758.
Published: 15 March 2002
... in the cytoplasm and basolateral membranes of all enterocytes and in the brush-border membrane of some cells, whereas NKCC immunofluorescence, demonstrating the presence of the Na + /K + /2Clcotransporter, was present in the cytoplasm and brush-border membrane. We conclude that the teleost intestine is capable...