..., compared with the ionic composition of the surrounding seawater. We pharmacologically investigated the role of Na + /H + exchangers (NHE) in intracellular pH regulation and midgut proton and sodium maintenance using the NHE inhibitor 5-( n -ethyl- n -isopropyl)amiloride (EIPA). Basolateral EIPA application...

... Carbon dioxide Disease vector NHE Rhesus glycoproteins Sodium chloride Like many aquatic invertebrate and vertebrate animals, the larvae of most mosquito species inhabit freshwater systems which can vary remarkably in water chemistry, including in ionic composition and pH ( Patrick et al...

... by the gills, but not the yolk sac skin, of early­ life stage rainbow trout, possibly resulting from the lack of the key transporter NHE2 in the yolk sac epithelium. Larval fish PNA + ionocyte Na + /H + -exchanger NHE Rhesus glycoproteins Ion regulation The relationship between sodium...

... Calliphora vicina salivary gland intracellular pH regulation Na + /H + antiporter NHE vacuolar H + -ATPase V-ATPase intracellular pH insect blowfly BCECF NH 4 Cl prepulse The tubular salivary glands in the blowfly Calliphora vicina consist of a single layer of epithelial cells...

... + suggests that C. v. hubbsi utilize one or more different proteins to acquire Na + in dilute freshwater compared with more saline waters. * Author for correspondence ( kbrix@rsmas.miami.edu ) 5 12 2011 © 2012. 2012 Na + uptake NHE NKCC mitochrondria-rich cells...

...Stefanos Dailianis; Efterpi Patetsini; Martha Kaloyianni SUMMARY This study investigated the role of Na + /H + exchanger(NHE) and signalling molecules, such as cAMP, PKC, PI 3-kinase, and immune defence enzymes, NADPH oxidase and nitric oxide synthase, in the induction of protein glutathionylation...

... of chloride interaction with neurotransmitter:v sodium symporters. Nature 449 , 726 -730. * Author for correspondence (e-mail: etana@vms.huji.ac.il ) 19 11 2008 2009 NhaA NHA NHE Na + /H + antiporters active transport membrane proteins Every cell and organelle...

... on NHE expression were investigated. The elevation of plasma cortisol using intraperitoneal implants caused a significant increase in NHE2 mRNA expression without affecting NHE3 mRNA or protein abundance. Thus, we suggest that NHE2 contributes to acid–base regulation during hypercapnia owing to its...

...; it provides weak HCO 3 – and weaker CO 3 2– anions to the lumen. The cationic pathway consists of H + V-ATPases and Na + /H + antiporters (NHAs), Na + /K + P-ATPases and Na + /H + exchangers (NHEs) along with several(Na + or K + ):amino acid +/– symporters,a.k.a. nutrient amino acid transporters (NATs...

... concanamycin A; (7) concanamycin A removes alkali-going components from multiphasic 5-HT-induced pH changes; (8) NHE activity and a Cl – -dependent process are involved in generating 5-HT-induced pH changes; (9) the salivary glands probably contain a Na + -driven amino acid transporter. We conclude that V...

... 20 8 2007 © The Company of Biologists Limited 2007 2007 sodium potassium exchanger alkalinization AgNHA NHA AgNHE NHE CHA CHE CPA2 African malaria mosquito All organisms regulate their cellular pH, volume and ionic composition. Na + and H + play key roles in all...

.... Hyperosmotic shrinkage by a calculated 25% activated a robust Na influx that in the first 30 min had a strong P O 2 dependency with maximal activation at low P O 2 values and a P 50 of ∼5.5 kPa. This activation was completely abolished by the Na/H exchanger (NHE) inhibitor EIPA (10 –4 mol l -1 ). Hyperosmotic...

... been suggested for Drosophila Malpighian tubules( Bertram and Wessing, 1994 ). By contrast, a Na + /H + exchange (NHE) has been proposed to play a major role in pH i regulation in Aedes and Rhodnius Malpighian tubules( Petzel, 2000 ; Ianowski and O'Donnell,2006 ). The epithelial cells...

... thiocyanate method( Zall et al., 1956 ). * Author for correspondence (e-mail: martint@ualberta.ca ) 11 11 2004 © The Company of Biologists Limited 2005 2005 dogfish Squalus acanthias gill acid-base regulation H + -ATPase Na + /K + -ATPase NHE acid infusion base infusion...