... of adenosine and guanosine was observed in hypoxic animals. Similarly, a decrease in both ATP and GTP levels occurred in hypoxic animals injected either with saline or with carbonic anhydrase. Interestingly, there was a highly significant relationship between ATP and GTP levels, indicating that they are under...

...René J. Feuerlein; Roy E. Weber * To whom reprint requests should be addressed. 17 12 1993 © 1994 by Company of Biologists 1994 anodic and cathodic haemoglobins ATP GTP nucleoside triphosphates fish blood oxygen affinity Oxygen transport to vertebrate...

... of intracellular Ca 2+ via a mechanism distinct from that activated by Ins P 3 . Using permeabilized neural or smooth muscle cells, application of submicromolar concentrations of GTP induces rapid release of Ca 2+ from a compartment that contains within it the Ins P 3 -releasable Ca 2+ pool. Although of similar...