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Keywords: GPCR
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Journal Articles
J Exp Biol (2023) 226 (19): jeb245859.
Published: 12 October 2023
.... In this Review, we highlight why this is complicated by the distinct evolutionary history of fish adrenergic receptors. Teleost Catecholamines GPCR Adrenergic receptors Evolution Genomics Novo Nordisk Fonden http://dx.doi.org/10.13039/501100009708 NNF19OC0055842 In response...
Journal Articles
J Exp Biol (2021) 224 (23): jeb226522.
Published: 29 November 2021
... pathways to open TRP channels. Melanopsin phototransduction cascades in some ipRGC subtypes open TRPC channels to depolarize the cell. Melanopsin is a canonical G-protein coupled receptor (GPCR), with seven transmembrane helices, an extracellular amino-terminus and an intracellular carboxy-tail...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (13): jeb242360.
Published: 2 July 2021
... and cartpt . This is the first time in any vertebrate species that changes in neuropeptide mRNA abundance have been assessed in response to agonists of these GPCRs. Finally, the changes described are comparable to those elicited by activation of FFA1 and FFA4 in the same species ( Velasco et al., 2020...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Exp Biol (2015) 218 (4): 562–571.
Published: 15 February 2015
... gene families. This review explores the early metazoan expansion of the largest integral transmembrane protein family, the G protein-coupled receptors (GPCRs), which serve as molecular targets for a large subset of neurotransmitters and neuropeptides in higher animals. GPCR repertories from four pre...
Journal Articles
J Exp Biol (2015) 218 (4): 618–628.
Published: 15 February 2015
... project. Competing interests The authors declare no competing or financial interests. © 2015. Published by The Company of Biologists Ltd 2015 Acoelomorpha Acoela Symsagittifera Xenoturbella Neural system Evolution bHLH GPCR cephalization Acoel flatworms together...
Includes: Supplementary data
Journal Articles
J Exp Biol (2009) 212 (13): 1973–1979.
Published: 1 July 2009
... to the G protein-coupled receptor(GPCR) superfamily; binding to odorants induces the production and amplification of second messengers, which lead to the depolarization of the neuron. The anatomical features of the insect olfactory circuit are similar to those of mammals, and until recently it was thought...
Journal Articles
J Exp Biol (2004) 207 (5): 743–748.
Published: 15 February 2004
.... † Author for correspondence (e-mail: taghertp@pcg.wustl.edu ) * Present address: Departments of Neuroscience and Pharmacology, The Ohio State University, Columbus, OH 43210, USA 3 12 2003 © The Company of Biologists Limited 2004 2004 neuropeptide GPCR receptor Drosophila...