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Keywords: GPCR
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Journal Articles
J Exp Biol (2021) 224 (23): jeb226522.
Published: 29 November 2021
... melanopsin phototransduction varies within other single ipRGC subtypes is an open question. Insights from other organisms clearly demonstrate the ability of melanopsin to be a promiscuous GPCR and support the novel research being done on melanopsin phototransduction in the mouse retina. As we gain more...
Includes: Supplementary data
Journal Articles
J Exp Biol (2021) 224 (13): jeb242360.
Published: 2 July 2021
... status of AMPKα and Akt, mRNA abundance of mTOR as well as in signalling pathways related to PLCβ and IP3 that might be involved in the action of both GPCRs. These results suggest that at least part of the capacity of fish brain to sense MCFA such as octanoate might relate to the function of GPR84...
Includes: Supplementary data
Journal Articles
J Exp Biol (2019) 222 (13): jeb201319.
Published: 5 July 2019
... ( Crassostrea gigas ) transcriptomic database GigaTON, we characterized seven G-protein-coupled receptors (GPCRs) named Cragi-CTR1–7 and phylogenetically related to chordate CT receptors (CTRs) and to protostome DH31 receptors. Two CT precursors (Cragi-CTP1 and Cragi-CTP2) containing two CT-type peptides...
Includes: Supplementary data
Journal Articles
J Exp Biol (2017) 220 (2): 294–303.
Published: 15 January 2017
...://www.biologists.com/user-licence-1-1/ Summary: An ancient duplication of the rhodopsin gene, rh1-2 , is a functional visual pigment and is expressed in retinal photoreceptors. Visual pigment Vision Gene duplication GPCR Teleost Vertebrate photoreception is mediated by opsins, which...
Includes: Supplementary data
Journal Articles
J Exp Biol (2015) 218 (4): 562–571.
Published: 15 February 2015
... gene families. This review explores the early metazoan expansion of the largest integral transmembrane protein family, the G protein-coupled receptors (GPCRs), which serve as molecular targets for a large subset of neurotransmitters and neuropeptides in higher animals. GPCR repertories from four pre...
Journal Articles
J Exp Biol (2015) 218 (4): 618–628.
Published: 15 February 2015
... (v27.0) ( Finn et al., 2014 ) hidden Markov models (HMM): PF00001 (7tm_1), PF00002 (7tm_2, Adhesion/Secretin), PF00003 (7tm_3, Glutamate), PF01534 (Frizzled) and PF05462 (Dicty_CAR) for the GPCR family; and PF00010 (HLH DNA-binding domain) for the HLH family. hmmsearch was run with the following...
Includes: Supplementary data
Journal Articles
J Exp Biol (2009) 212 (13): 1973–1979.
Published: 1 July 2009
... to the G protein-coupled receptor(GPCR) superfamily; binding to odorants induces the production and amplification of second messengers, which lead to the depolarization of the neuron. The anatomical features of the insect olfactory circuit are similar to those of mammals, and until recently it was thought...
Journal Articles
J Exp Biol (2004) 207 (5): 743–748.
Published: 15 February 2004
... in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 100 , 6198 -6203. Johnson, E. C., Bohn, L. M., Barak, L. S., Birse, R. T.,Nässel, D. R., Caron, M. G. and Taghert, P. H. ( 2003b ). Identification of Drosophila neuropeptide receptors by GPCR-βarrestin-2 interactions. J. Biol. Chem. 278...