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Keywords: DNA demethylationClose
Journal: Journal of Experimental Biology
J Exp Biol (2015) 218 (1): 14–20.
Published: 1 January 2015
... of genetic mutation or may allow mutations to happen in the context of, for example, genomic hypomethylation. DNA demethylation and reprogramming are necessary to break the epigenetic barrier in order to transit between different cell identity states but the presence of initiating signals is necessary...