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J Exp Biol (2019) 222 (11): jeb192096.
Published: 31 May 2019
...]polyethylene glycol (MW 400 kDa, PEG-400). Concurrently, mRNA abundance of gr2 and 11βhsd increased, indicating a possible compensatory response to mr -KD. Transcript abundance of claudin ( cldn ) -6 , -8d , - 23a and -28b decreased while that of cldn-20a increased in mr -KD preparations. Cortisol-induced...
Includes: Supplementary data
J Exp Biol (2019) 222 (3): jeb192245.
Published: 1 February 2019
... tricellulin (Tric) as well as the bicellular TJ (bTJ) proteins occludin (Ocln), claudin (Cldn)-1, Cldn-4 and the scaffolding TJ protein zonula occludens 1 (ZO-1). However, while Tric protein abundance increased in accord with changes in transcript abundance, protein abundance of Cldn-1 was significantly...
J Exp Biol (2014) 217 (19): 3483–3492.
Published: 1 October 2014
..., we investigated tight junction gene expression. M. lucifugus had higher expression of claudin-1 and claudin-15, and lower expression of claudin-2 relative to P. leucopus . Expression of claudin-7 and occludin did not differ among species. Taken together, our results support the hypothesis that bats...
J Exp Biol (2014) 217 (10): 1667–1681.
Published: 15 May 2014
... on a permeable substrate), changes in TJ protein mRNA abundance were conservative, despite paracellular marker flux decreasing by orders of magnitude. In both cases significant changes in claudin-8b, -8d, -27b, -28b and - 32a transcript abundance were observed, suggesting that temporal alterations...
J Exp Biol (2013) 216 (21): 4065–4070.
Published: 1 November 2013
... absorptive demand. We measured absorption of l -arabinose, intestinal size and gene expression of several tight junction proteins (claudin-2, claudin-4, claudin-15 and ZO-1) at three time points: pre-exposure, and after 1 day and 2 weeks of cold exposure. Cold exposure increased food intake by 62% after 2...
Friederike Stumpff, Maria-Ifigenia Georgi, Lars Mundhenk, Imtiaz Rabbani, Michael Fromm, Holger Martens, Dorothee Günzel
J Exp Biol (2011) 214 (17): 2871–2882.
Published: 1 September 2011
... characterized by transepithelial resistance (TER) measurements and patch clamping. Cells developed TER values of 729±134 Ω cm 2 (rumen) and 1522±126 Ω cm 2 (omasum). Both primary cells and source epithelia of rumen and omasum expressed cytokeratin, occludin and claudins 1, 4 and 7 (but not claudins 2, 3, 5, 8...
Includes: Supplementary data
J Exp Biol (2011) 214 (14): 2308–2318.
Published: 15 July 2011
... of select tight junction (TJ) proteins were examined in response to cortisol, dexamethasone (a GR agonist) and RU486 (as a MR agonist). Occludin and claudin-7, -8d, -12 and -31 mRNA were significantly elevated in response to cortisol, dexamethasone or RU486 treatment. Claudin-3a mRNA was significantly...