...Krystle Talbot; Raymond W. M. Kwong; Kathleen M. Gilmour; Steve F. Perry ABSTRACT The present study tested the hypothesis that zebrafish ( Danio rerio ) aquaporin-1a1 (AQP1a1) serves as a multi-functional channel for the transfer of the small gaseous molecules, CO 2 and ammonia, as well as water...

...Juan Antonio Martos-Sitcha; Marco Antonio Campinho; Juan Miguel Mancera; Gonzalo Martínez-Rodríguez; Juan Fuentes ABSTRACT Aquaporins (AQPs) are specific transmembrane water channels with an important function in water homeostasis. In terrestrial vertebrates, AQP2 function is regulated...

...Steffen S. Madsen; Joanna Bujak; Christian K. Tipsmark We investigated the salinity-dependent expression dynamics of seven aquaporin paralogs ( aqp1a, aqp3a, aqp7, aqp8ab, aqp10a, aqp10b and aqp11a ) in several tissues of euryhaline Japanese medaka ( Oryzias latipes ). All paralogs except aqp7...

...Morten B. Engelund; François Chauvigné; Birgitte Mønster Christensen; Roderick Nigel Finn; Joan Cerdà; Steffen S. Madsen SUMMARY Aquaporins may facilitate transepithelial water absorption in the intestine of seawater (SW)-acclimated fish. Here we have characterized three full-length aqp8 paralogs...

...Y. Ogushi; D. Kitagawa; T. Hasegawa; M. Suzuki; S. Tanaka SUMMARY The ventral pelvic skin of the tree frog Hyla japonica expresses two kinds of arginine vasotocin (AVT)-stimulated aquaporins (AQP-h2 and AQP-h3), which affect the capacity of the frog's skin to absorb water. As such, it can be used...

...A. S. Verkman SUMMARY There is considerable potential for translating knowledge of aquaporin structure, function and physiology to the clinic. One area is in aquaporin-based diagnostics. The discovery of AQP4 autoantibodies as a marker of the neuromyelitis optica form of multiple sclerosis has...

... to the presence of aquaporins (AQPs), the ubiquitous water transport proteins. There are 13 known human AQPs, and they are tissue and even membrane specific. It is now clear that the number and type of AQPs within a membrane are the major determinants of its water transport capacity. There are many gene homologs...

...Makoto Kubota; Takahiro Hasegawa; Takashi Nakakura; Haruna Tanii; Masakazu Suzuki; Shigeyasu Tanaka SUMMARY A new toad aquaporin (AQP) cDNA was cloned from a cDNA library constructed from the ventral skin of Xenopus laevis . This AQP ( Xenopus AQP-x5) consisted of 273 amino acid residues...

...Soichi Watanabe; Toyoji Kaneko; Katsumi Aida SUMMARY We have cloned a homologue of mammalian aquaporin-3 (AQP3) from gills of Mozambique tilapia using a reverse transcription-polymerase chain reaction(RT-PCR). The deduced amino acid sequence shared 64–75% homology with other vertebrate AQP3...

...C. R. A. Santos; M. D. Estêvão; J. Fuentes; J. C. R. Cardoso; M. Fabra; A. L. Passos; F. J. Detmers; P. M. T. Deen; J. Cerdà; D. M. Power SUMMARY The aquaporins (formerly called the major intrinsic protein family) are transmembrane channel proteins. The family includes the CHIP group, which...

... in biological performance. Here, we examine the phenotypic flexibility of water flux rate, urine osmolality and the expression of kidney aquaporins (AQP; or water channels) in free-ranging Octodon degus , a South American desert-dwelling rodent, through an integrative study at cellular, systemic and organismal...

... aquaporin Paramecium multimicronucleatum The contractile vacuole complex is a membrane-bound osmoregulatory organelle observed in freshwater protozoa and sponges ( Jeeps, 1947 ; Patterson, 1980 ). The organelle of Paramecium multimicronucleatum consists of a central contractile vacuole (CV...