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Keywords: miRNA
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Journal Articles
J Cell Sci (2021) 134 (9): jcs253914.
Published: 17 May 2021
...Bartika Ghoshal; Edouard Bertrand; Suvendra N. Bhattacharyya ABSTRACT MicroRNAs (miRNAs), the tiny regulators of gene expression, can be transferred between neighbouring cells via extracellular vesicles (EVs) to control the expression of genes in both donor and recipient cells. How the EV-derived...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2020) 133 (24): jcs250241.
Published: 29 December 2020
...Susanta Chatterjee; Yogaditya Chakrabarty; Saikat Banerjee; Souvik Ghosh; Suvendra N. Bhattacharyya ABSTRACT Defective intracellular trafficking and export of microRNAs (miRNAs) have been observed in growth-retarded mammalian cells having impaired mitochondrial potential and dynamics. Here, we...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (15): jcs243162.
Published: 11 August 2020
... postnatally, lifelong plasticity facilitates stimulus-dependent adaptation. Functional adaptation requires molecular adaptation, which is partially provided by miRNA-mediated post-transcriptional regulation. miR-206 is a muscle-specific miRNA enriched in slow muscles. We investigated whether miR-206 drives...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2018) 131 (4): jcs202002.
Published: 14 February 2018
...) granules. RNP granules assemble through a concentration-dependent liquid–liquid phase separation of RNA-binding proteins that contain low-complexity sequence domains (LCDs). Interestingly, many factors that regulate microRNA (miRNA) biogenesis and alternative splicing are RNA-binding proteins that contain...
Journal Articles
J Cell Sci (2016) 129 (7): 1477–1489.
Published: 1 April 2016
... that Gliotactin levels are also regulated at the mRNA level by micro (mi)RNA-mediated degradation and that miRNAs are targeted to a short region in the 3′UTR that includes a conserved miR-184 target site. miR-184 also targets a suite of septate junction proteins, including NrxIV, coracle and Mcr. miR-184...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2015) 128 (17): 3197–3209.
Published: 1 September 2015
... largely unknown. Intriguingly, we found that the dynamin (DNM) genes, a GTPase family of proteins responsible for endocytosis in eukaryotic cells, encode the conserved miR-199a and miR-199b family of miRNAs within their intronic sequences. Here, we demonstrate that miR-199a and miR-199b regulate endocytic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (8): 1607–1616.
Published: 15 April 2015
...Luba Farberov; Eytan Herzig; Shira Modai; Ofer Isakov; Amnon Hizi; Noam Shomron MicroRNAs (miRNAs) are short non‐coding RNAs that play a central role in the regulation of gene expression by binding to target mRNAs. Several studies have revealed alterations in cellular miRNA profiles following HIV‐1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (4): 804–814.
Published: 15 February 2015
... interests The authors declare no competing or financial interests. 29 09 2014 12 12 2014 © 2015. Published by The Company of Biologists Ltd 2015 IGF1R Endometrium Implantation Embryo miR-145 miRNA Implantation failure is a major cause of infertility in the developed...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (20): 4494–4506.
Published: 15 October 2014
... in obstructed kidney. This study reveals a new mechanism whereby microvesicle-mediated communication of miRNA between fibroblasts and tubular cells is involved in regulating tubular cell apoptosis, which might provide new therapeutic targets for renal tubulointerstitial fibrosis. * These authors...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2013) 126 (15): 3401–3408.
Published: 1 August 2013
...Biao Yan; Ban Liu; Chang-Dong Zhu; Kang-Le Li; Li-Jia Yue; Jin-Liang Zhao; Xiao-Ling Gong; Cheng-Hui Wang Summary MicroRNAs (miRNAs) are endogenous small non-coding RNAs that play crucial roles in numerous biological processes. However, the role of miRNAs in skin color determination in fish has...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (13): 2867–2876.
Published: 1 July 2013
...Lihi Ninio-Many; Hadas Grossman; Noam Shomron; Dana Chuderland; Ruth Shalgi Summary Fyn, a member of the Src family kinases (SFKs), has a pivotal role in cell adhesion, proliferation, migration and survival, and its overexpression is associated with several types of cancer. MicroRNAs (miRNAs) play...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (4): 606–618.
Published: 15 February 2010
...Stephanie B. Greene; Preethi H. Gunaratne; Scott M. Hammond; Jeffrey M. Rosen In an effort to understand the potential role of microRNAs (miRNAs) in mammary-gland stem or progenitor cells, miRNA microarrays were performed on subpopulations of the mouse mammary epithelial cell (MEC) line COMMA-DβGeo...
Includes: Supplementary data