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Keywords: cytoskeleton
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Journal Articles
J Cell Sci (2024) 137 (3): jcs261740.
Published: 12 February 2024
... involved in the regulation of microtubule dynamics and function in eukaryotes. In the protozoan parasite Trypanosoma brucei , the microtubule cytoskeleton is essential for cell motility and maintaining cell shape. In a previous study, we showed that T. brucei TTLL6A and TTLL12B are required to regulate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2024) 137 (3): jcs260481.
Published: 8 February 2024
... in autophagy contributes to disease. Adaptor proteins Autophagy Cytoskeleton Dynein Kinesin Myosin Jawaharlal Nehru Centre for Advanced Scientific Research http://dx.doi.org/10.13039/501100005116 Science and Engineering Research Board http://dx.doi.org/10.13039/501100001843...
Journal Articles
In collection:
Cytoskeleton , Imaging
J Cell Sci (2024) 137 (2): jcs261389.
Published: 18 January 2024
...Thomas A. Phillips; Stefania Marcotti; Susan Cox; Maddy Parsons ABSTRACT The actin cytoskeleton plays a critical role in cell architecture and the control of fundamental processes including cell division, migration and survival. The dynamics and organisation of F-actin have been widely studied...
Journal Articles
Journal Articles
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Cytoskeleton
J Cell Sci (2023) 136 (19): jcs259448.
Published: 10 October 2023
..., curvature sensitivity and the resulting membrane deformations. Membrane Cytoskeleton Septins Agence Nationale de la Recherche http://dx.doi.org/10.13039/501100001665 ANR-13-JSV8-0002-01 ANR-20-CE11-0014-01 ANR-10-IDEX-0001-02 ANR-11-LABX0038 Sorbonne Université http...
Journal Articles
J Cell Sci (2023) 136 (18): jcs261122.
Published: 28 September 2023
.... The mechanism by which paxillin mediated this effect appeared to be through the actin cytoskeleton, which signals to the ERK pathway and induces ECM protein production. These data highlight a novel role for paxillin in HSC biology and fibrosis. * Author for correspondence ( rockey@musc.edu ) Handling...
Includes: Supplementary data
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2023) 136 (18): jcs260985.
Published: 25 September 2023
... emerges from cell and tissue interactions. Shear stress Fluid shear stress Biomechanics Cytoskeleton European Research Council http://dx.doi.org/10.13039/100010663 Horizon 2020 http://dx.doi.org/10.13039/100010661 950254 EMBO http://dx.doi.org/10.13039...
Journal Articles
J Cell Sci (2023) 136 (17): jcs261301.
Published: 8 September 2023
...) poses an increasing threat to human health. We provide evidence to support a positive correlation between host cell contractility and ZIKV infection efficacy. Cytoskeleton Actomyosin Cell contractility Zika virus Host–pathogen interaction Key Research and Development Program, Ministry...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (16): jcs261356.
Published: 18 August 2023
.... Biophys. Res. Commun. 265 , 112 - 115 . 10.1006/bbrc.1999.1635 Dewane , G. , Salvi , A. M. and Demali , K. A. ( 2021 ). Fueling the cytoskeleton - links between cell metabolism and actin remodeling . J. Cell Sci. 134 , jcs248385 . 10.1242/jcs.248385 Engl , E...
Journal Articles
J Cell Sci (2023) 136 (14): jcs260902.
Published: 24 July 2023
...Mayis Kaba; Amado Carreras-Sureda; Paula Nunes-Hasler; Nicolas Demaurex ABSTRACT Changes in membrane phosphoinositides and local Ca 2+ elevations at sites of particle capture coordinate the dynamic remodeling of the actin cytoskeleton during phagocytosis. Here, we show that the phosphatidylinositol...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Cytoskeleton , Motors
J Cell Sci (2023) 136 (10): jcs261100.
Published: 25 May 2023
..., distribution and reproduction in any medium provided that the original work is properly attributed. Highlighted Article: GIPC3 couples the molecular motors MYO6 and MYO18A to actin cytoskeleton structures in hair cells. GIPC3 is necessary for shaping cuticular plate of the hair cell and hence...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2023) 136 (6): jcs260684.
Published: 20 March 2023
...Ziyi Feng; Zhenfeng Mao; Ziwei Yang; Xiaowei Liu; Fumihiko Nakamura ABSTRACT Filamin A (FLNA) is an actin crosslinking protein that mediates mechanotransduction. External and internal mechanical forces, through the actin cytoskeleton, can induce conformational changes of the FLNA molecule to expose...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (5): jcs260749.
Published: 2 March 2023
... or extracellular environment, whereas degradation results from delivery of the cargo to the lysosome ( Redpath et al., 2020 ). Coupling of endocytosis and endosomal trafficking to the actin and microtubule (MT) cytoskeleton is essential for regulation of cargo sorting for these recycling or degradative fates...
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2022) 135 (22): jcs259769.
Published: 18 November 2022
... the sophisticated force-generation machinery of the cell, the cytoskeleton. All regions of the cell are connected via mechanical linkages, enabling the whole cell to function as a mechanical system. In this Review, we define some of the key concepts of how this machinery functions, highlighting the critical...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (11): jcs259893.
Published: 9 June 2022
... organizers of the cytoskeleton, organelles and flagellum positioning ( Lacomble et al., 2009 , 2010 ). During maturation, the pro-BB acquires appendages, essential structures for docking to the plasma membrane and recruitment of the IFT proteins ( Stephan et al., 2007 ; Morga and Bastin, 2013 ; Wei et al...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (8): jcs259493.
Published: 3 May 2022
... ). The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton . J. Biol. Chem. 286 , 26743 - 26753 . 10.1074/jbc.M111.233700 Madsen , C. D. and Sahai , E. ( 2010 ). Cancer dissemination—lessons from...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton , Imaging
J Cell Sci (2022) 135 (7): jcs259234.
Published: 8 April 2022
..., frequently contained lumenal particles and exhibited lattice defects. Investigation of the effect of absence of doublecortin, a neurodevelopmental cytoskeleton regulator, on growth cone cytoskeleton showed no major anomalies in overall growth cone organisation or in F-actin subpopulations. However, our data...
Includes: Supplementary data