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In collection:Cell Migration
J Cell Sci (2023) 136 (3): jcs260591.
Published: 2 February 2023
...Shigehiko Yumura; Masaki Nakano; Aika Honda; Yuuki Hashimoto; Tomo Kondo ABSTRACT Cyclic guanosine 3′,5′-monophosphate (cGMP) is a ubiquitous important second messenger involved in various physiological functions. Here, intracellular cGMP (cGMPi) was visualized in chemotactic Dictyostelium cells...
Includes: Supplementary data
J Cell Sci (2010) 123 (6): 837–841.
Published: 15 March 2010
...-induced serine phosphorylation of the PTP3 protein tyrosine phosphatase inhibits its activity towards STATc. We show that two serine residues in PTP3, S448 and S747, are rapidly phosphorylated after osmotic stress. cGMP is a second messenger for hyperosmotic stress response and 8-bromo-cGMP, a membrane...
Elisabetta Ciani, Vincenzo Calvanese, Christophe Crochemore, Renata Bartesaghi, Antonio Contestabile
J Cell Sci (2006) 119 (15): 3161–3170.
Published: 1 August 2006
... into DNA. This was accompanied by increased expression of Myc, a transcription factor essential for cerebellar development, and of the cell cycle regulating gene, cyclin D1. These effects were mediated downstream by the nitric oxide-dependent second messenger, cGMP. Schedules of pharmacological...
Leonard Bosgraaf, Arjen Waijer, Ruchira Engel, Antonie J. W. G. Visser, Deborah Wessels, David Soll, Peter J. M. van Haastert
J Cell Sci (2005) 118 (9): 1899–1910.
Published: 1 May 2005
... and adhesive owing to an increased number of substrate-attached pseudopodia. This GbpD phenotype is not dependent on intracellular cGMP or cAMP, like its mammalian homolog PDZ-GEF. Previously we showed that GbpC is a high-affinity cGMP-binding protein that acts via myosin II. We conclude that cGMP activates...
J Cell Sci (2002) 115 (18): 3675–3682.
Published: 15 September 2002
...-depleted cells exhibited reduced viability in response to osmotic shock. The accumulation of cGMP in response to 0.4 M sorbitol was reduced after rapA antisense RNA induction and was enhanced in cells expressing the constitutively activated Rap1(G12V) protein, suggesting a role for Rap1 in the generation...
Kenji Hasegawa, Hiroto Kikuchi, Shigeo Ishizaki, Akiko Tamura, Yasuo Tsukahara, Yasuo Nakaoka, Eiichi Iwai, Toshiro Sato
J Cell Sci (1999) 112 (2): 201–207.
Published: 15 January 1999
...Kenji Hasegawa; Hiroto Kikuchi; Shigeo Ishizaki; Akiko Tamura; Yasuo Tsukahara; Yasuo Nakaoka; Eiichi Iwai; Toshiro Sato ABSTRACT The circadian dynamics of cyclic adenosine 3′,5′-monophosphate (cAMP) and cyclic guanosine 3′,5′-monophosphate (cGMP) were simulated in Paramecium multimicronucleatum...
J Cell Sci (1993) 105 (1): 255–261.
Published: 1 May 1993
... to discriminate between both fluxes. Perme-abilised cells still showed the cAMP-induced ca 2+ uptake. The flux across the plasma membrane was more sensitive to Bα 2+ and Mn 2+ , respectively, than ca 2+ sequestration. We have shown previously, using stm F mutants, that cGMP regulates ca 2+ influx. We confirmed...
J Cell Sci (1993) 104 (1): 197–202.
Published: 1 January 1993
... is involved in signal transduction, we have tested the effect of PAF on some cellular responses which are regulated by cAMP, such as spontaneous light-scattering oscillations of suspended cells, cAMP relay, transient increases of cGMP level, and extracellular calcium uptake. Our results show that PAF...