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Keywords: Z-disc
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Journal Articles
J Cell Sci (2022) 135 (20): jcs260179.
Published: 13 October 2022
... system is held in place by a structure called the Z-disc, which anchors the actin filaments. Myosin filaments, in turn, are anchored to another structure called the M-line. Most of the complex architecture of myofibrils can be reduced to studying the Z-disc, and recently, important advances regarding...
Journal Articles
Journal Articles
J Cell Sci (2011) 124 (20): 3464–3476.
Published: 15 October 2011
... microscopy and quantitative analysis, we demonstrate that expression of the mutant desmin K190A in primary myocytes results in a significant reduction in assembled endogenous nebulin and desmin at the Z-disc. Non-uniform actin filaments were markedly prevalent in myocytes expressing GFP-tagged desmin K190A...
Includes: Supplementary data
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