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Keywords: WWP2
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Journal Articles
In collection:
Ubiquitin and Protein Degradation
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (24): jcs260284.
Published: 15 December 2022
... by liquid–liquid phase separation. An intrinsically disordered region (IDR) at the N-terminus is essential for Dvl2 phase separation. Importantly, we identified the HECT-E3 ligase WWP2 as an essential driver of Dvl2 phase separation in vitro and in cells. We demonstrated that ubiquitylation of Dvl2 through...
Includes: Supplementary data
