1-6 of 6
Keywords: WAVE2
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2016) 129 (14): 2829–2840.
Published: 15 July 2016
... in IRTKS-knockout (KO) cells. To further define the Rif–IRTKS signaling pathway, we identify Eps8 and WAVE2 (also known as WASF2) as IRTKS interactors. We find that Eps8 regulates the size and number of dorsal filopodia and membrane ruffles downstream of Rif–IRTKS signaling, whereas WAVE2 modulates dorsal...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (3): 379–390.
Published: 1 February 2008
... substrate protein 53 (IRSp53) or a complex of proteins containing Abelson interactor protein 1 (Abi1) mediates the interaction of WAVE2 and Rac. Depletion of endogenous IRSp53 by RNA-mediated interference (RNAi) in a RAW/LR5 macrophage cell line resulted in a significant reduction of Rac1Q61L-induced...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (23): 4144–4154.
Published: 1 December 2007
...Christopher M. Danson; Shirin M. Pocha; Graham B. Bloomberg; Giles O. Cory The WAVE family of proteins has long been implicated in the stimulus-dependent generation of lamellipodia at the leading edge of migrating cells, with WAVE2 in particular implicated in the formation of peripheral ruffles...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (19): 3465–3474.
Published: 1 October 2007
... knockdown inhibited EGF-stimulated activation of PI 3-kinase at early (within 1 minute) but not late (within 3 minutes) time points. Membrane targeting of N-WASP, WAVE2 and IRSp53 were also inhibited. Effects on WAVE2 were not owing to Rac1 inhibition, because WAVE2 recruitment is unaffected by Rac1...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (8): 1436–1446.
Published: 15 April 2007
... of Abi1. This is accompanied by a subcellular translocation of Abi1/WAVE2 to a site adjacent to membrane, where an F-actin-enriched structure containing the adhesion molecules such as β1-integrin, paxillin and vinculin is assembled. Bcr-Abl-induced membrane translocation of Abi1/WAVE2 requires direct...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (22): 5369–5379.
Published: 15 November 2005
... identified, no data was available regarding the function of WASP family verprolin-homologous (WAVE) proteins in this cell type. We found that WAVE2 was the predominant isoform to be expressed in primary macrophages and in cells derived from the murine monocyte/macrophage RAW264.7 cell line (RAW/LR5). CSF-1...
Includes: Supplementary data