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Keywords: SNAP-25
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Journal Articles
J Cell Sci (2017) 130 (11): 1877–1889.
Published: 1 June 2017
... that Snap-25 -null mutant (SNAP-25 KO) neurons, previously shown to degenerate after 4 days in vitro (DIV), contain fewer DCVs and have reduced DCV fusion probability in surviving neurons at DIV14. At DIV3, before degeneration, SNAP-25 KO neurons show normal DCV fusion, but one day later fusion...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2008) 121 (20): 3413–3421.
Published: 15 October 2008
... syntaxin 4 and cytoplasmic murine CENPF, a protein previously demonstrated to associate with the microtubule network and SNAP-25. The binding domain for syntaxin 4 in CENPF was defined by yeast two-hybrid assay and co-immunoprecipitation. Confocal analyses in cell culture reveal a high degree...
Journal Articles
J Cell Sci (2004) 117 (6): 955–966.
Published: 22 February 2004
...Helmut Kubista; Hannah Edelbauer; Stefan Boehm The core complex, formed by the SNARE proteins synaptobrevin 2, syntaxin 1 and SNAP-25, is an important component of the synaptic fusion machinery and shows remarkable in vitro stability, as exemplified by its SDS-resistance. In western blots...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2002) 115 (3): 667–673.
Published: 1 February 2002
... and in which SNAP-25 and syntaxin predominate over synaptobrevin. Their formation increased upon Ca 2+ -stimulated exocytosis; notably, the 2D protocol proved much superior to 1D SDS-PAGE for the detection of large complexes and revealed that for forms with relative molecular mass greater than 100,000...
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1997) 110 (4): 505–513.
Published: 15 February 1997
...Guangyi Wang; Joan W. Witkin; Gianming Hao; Vytas A. Bankaitis; Philipp E. Scherer; Giulia Baldini ABSTRACT SNAP-25 is a synaptosomal associated protein localized at the plasma membrane of nerve terminals. SNAP-25 associates with syntaxin 1 and vesicle-associated membrane protein-2 (VAMP-2...
Journal Articles
J Cell Sci (1996) 109 (12): 2875–2884.
Published: 1 December 1996
... are Zn 2+ -dependent proteases that cleave VAMP/synaptobrevin and SNAP-25, two proteins which can form a ternary complex (termed the SNARE complex) with syntaxin and have been implicated in the docking of synaptic vesicles at the plasma membrane. The onset of toxin-induced inhibition of neurotransmitter...
Journal Articles