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Keywords: Rho proteins
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Journal Articles
J Cell Sci (2003) 116 (11): 2247–2260.
Published: 1 June 2003
... factor (VEGF) production. In this study, we investigated the activities of Rho proteins, which are key regulators of cytoskeleton organization during hypoxia in renal cell carcinoma. Caki-1 cells were exposed to hypoxia (1% O 2 ) and exhibited increased Cdc42, Rac1 and RhoA protein expression...
Journal Articles
J Cell Sci (2002) 115 (12): 2475–2484.
Published: 15 June 2002
... stimulation of GTP-bound Rho proteins was determined following normalization against total GTPases. Fig. 2. Temporal activation of Cdc42 and Rac1 by thrombin and S1P. Confluent monolayers of serum-starved HUVECs were treated for the times indicated with 10 nM thrombin or 0.5 μM SIP. Western blot analyses...