... in biological triplicates and transcript abundance assessed by RNA-sequencing (RNA-seq). In total, abundance profiles were obtained for over 13,000 transcripts. In line with previous findings ( Na et al., 2007 ; Mathavarajah et al., 2018 ), differential expression analysis using a false discovery rate (FDR...

.... ( 2017 ). Rna-seq differential expression analysis: an extended review and a software tool . PLoS ONE 12 , e0190152 . 10.1371/journal.pone.0190152 Korthauer , K. , Kimes , P. K. , Duvallet , C. , Reyes , A. , Subramanian , A. , Teng , M. , Shukla , C. , Alm...

... as early as postnatal day 12. RNA-seq analysis showed significant gene enrichment of biological processes related to transcriptional regulation, cell cycle, DNA damage/repair and autophagy in Lbh -null OHCs. In addition, Wnt and Notch pathway-related genes were found to be dysregulated in Lbh -deficient...

.... Staufen1 RNA Localization Post-transcriptional regulation Mitotic spindle RNA-Seq Ribosomal RNA The localization of RNA molecules to specific subcellular compartments, a cellular mechanism that is crucial for normal progression of several biological processes, functions to spatiotemporally...

... invasion. Summary: Image-guided capture and sequencing of invasive cancer cells reveals novel leader- and follower-specific gene mutations, highlighting an important relationship between genomic and phenotypic heterogeneity during collective invasion. Metastasis Lung cancer RNA-seq Mutation...