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Keywords: Protein sorting
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Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2022) 135 (10): jcs260059.
Published: 19 May 2022
... and transport activity. Major facilitator superfamily MFS Transporters Monocarboxylic acids Endocytosis Arrestin Cytosolic termini Protein sorting Protein turnover Substrate specificity Ubiquitylation Fundação para a Ciência e a Tecnologia http://dx.doi.org/10.13039/501100001871...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (20): jcs258894.
Published: 21 October 2021
... metabolism in AD. Sortilin is a member of the vacuolar protein sorting 10 protein (VPS10P) domain receptor family, a group of specialized receptors involved in endocytosis and intracellular sorting of ligands (reviewed in Carlo et al., 2014 ). Binding of lipid-laden apoE4 to sortilin on the cell surface...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (6): jcs252189.
Published: 26 March 2021
... and Priori, 2006 ). Loss-of-function is frequently caused by defective Na V 1.5 trafficking and localization to the cell surface ( Rook et al., 2012 ). Protein sorting Palmitoylation Voltage-gated sodium channel SCN2B Na V 1.5 Cardiac arrhythmia Summary: The voltage-gated sodium...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (10): jcs211110.
Published: 16 May 2018
... machinery can, in principle, process mitochondrial proteins but, under normal conditions, active mitochondrial targeting pathways dominate the kinetic competition against GET recognition. ER GET Mitochondria Outer membrane Protein sorting Tail-anchor Eukaryotic cells face the challenge...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (2): jcs203695.
Published: 29 January 2018
...Nicole Heucken; Rumen Ivanov; Jenny Russinova ABSTRACT Protein sorting in the endomembrane system is responsible for the coordination of cellular functions. Plant intracellular trafficking has its own unique features, which include specific regulatory aspects of endosomal sorting and recycling...
Journal Articles
J Cell Sci (2016) 129 (1): 95–107.
Published: 1 January 2016
... (TMD) dominates discussion about determinants required for protein sorting to the plasma membrane. Transmembrane adaptor proteins (TRAP) are involved in signalling events which take place at the plasma membrane. Members of this protein family have TMDs of varying length. We were interested in whether...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (22): 4160–4170.
Published: 15 November 2015
... is regulated by p150 glued to coordinate protein sorting and transport carrier formation with the subsequent long-range transport towards the Golgi complex along microtubules. In these cell lines, the YFP-tagged SAR1, SEC23 or SEC31 colocalized extensively with endogenous SEC31 (see Fig. 1 ). No apparent...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (7): 1576–1582.
Published: 1 April 2013
... of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8.   Genetics   147 , 1569 – 1584 . Roberg   K. J. , Rowley   N. , Kaiser   C. A. ( 1997b ). Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae.   J. Cell Biol.   137 , 1469 – 1482...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (3): 329–338.
Published: 1 February 2008
... transport pathways to the yeast vacuole. Microbiol. Mol. Biol. Rev. 62 , 230 -247. Cereghino, J. L., Marcusson, E. G. and Emr, S. D. ( 1995 ). The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function...
Journal Articles
J Cell Sci (2007) 120 (14): 2378–2389.
Published: 15 July 2007
... was carried out as previously described by Reddy and Seaman ( Reddy and Seaman, 2001 ). E-mail: mnjs100@cam.ac.uk 12 5 2007 © The Company of Biologists Limited 2007 2007 Trans-Golgi network Endosomes CIMPR Protein sorting The function of the different organelles...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (11): 2173–2183.
Published: 1 June 2006
... 18 4 2006 © The Company of Biologists Limited 2006 2006 ER-exit sites ER-to-Golgi transport ERGIC-53 Protein sorting COPI COPII Tethering Fusion The ER-Golgi intermediate compartment (ERGIC) is a complex membrane system between the rough endoplasmic reticulum (ER...
Journal Articles
J Cell Sci (2005) 118 (23): 5499–5511.
Published: 1 December 2005
... Trypanosome Glycosylphosphatidylinositol Flagellar pocket Transferrin receptor Protein sorting BS221 cells (∼5×10 7 ), grown in HMI9 media supplemented with either 10% canine or fetal bovine serum for 48 hours, were washed with HEPES buffered-saline (HBS) and resuspended in 0.8 ml HMI9 media...
Journal Articles
J Cell Sci (2004) 117 (25): 5955–5964.
Published: 1 December 2004
... by annexin oligomers should cluster raft components in the exoplasmic leaflet. © The Company of Biologists Limited 2004 Protein sorting Epithelial cells Rafts Apical membrane Most cell types generated by multicellular organisms are polarized. A characteristic feature of polarized cells...
Journal Articles
J Cell Sci (2002) 115 (1): 185–194.
Published: 1 January 2002
... determine the sorting of Lamp 1 and LAP in endosomes, mediating either the direct or the indirect pathway to lysosomes. *Address for correspondence (e-mail: shoenin@gwdg.de ) 21 9 2001 © The Company of Biologists Limited 2002 2002 Endosome Protein sorting Cytoplasmic tail...
Journal Articles
J Cell Sci (1993) 1993 (Supplement_17): 21–26.
Published: 1 December 1993
... of a particular serine. Key words: transcytosis, protein sorting, sorting signals tein transport processes that have been studied in polarized cells (Simons and Wandinger-Ness, 1990; Bomsel and Mostov, 1991). One such transport process is the targeting of membrane proteins to different poles of the cell. In most...
Journal Articles
J Cell Sci (1993) 1993 (Supplement_17): 27–32.
Published: 1 December 1993
... with the cytoso­ lic side of the membrane. Key words: protein sorting, heterotrimeric G proteins, epithelial cells THE POLARITY PATHWAYS In polarized epithelial cells, the plasma membrane is divided into two domains, apical and basolateral, which are distinct in their lipid and protein compositions. Most...
Journal Articles
J Cell Sci (1991) 1991 (Supplement_14): 143–145.
Published: 1 January 1991
... consensus elements characteristic of GTP-binding proteins, and biochemical results support a role for GTP in dynamin function. Dynamin is also homologous to the Mx proteins, involved in interferon-induced viral resistance, and the product of the yeast VPS1 gene, involved in vacuolar protein sorting...