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Keywords: Prostate cancer
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Journal Articles
J Cell Sci (2021) 134 (14): jcs258332.
Published: 28 July 2021
...Fatma Özgün; Zeynep Kaya; Tunç Morova; Bart Geverts; Tsion E. Abraham; Adriaan B. Houtsmuller; Martin E. van Royen; Nathan A. Lack ABSTRACT Androgen receptor (AR) splice variants are proposed to be a potential driver of lethal castration-resistant prostate cancer. AR splice variant 7 (ARv7...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (24): 4629–4641.
Published: 15 December 2015
...Robert L. Satcher; Tianhong Pan; Mehmet A. Bilen; Xiaoxia Li; Yu-Chen Lee; Angelica Ortiz; Andrew P. Kowalczyk; Li-Yuan Yu-Lee; Sue-Hwa Lin ABSTRACT Cadherin-11 (Cad11) cell adhesion molecule plays a role in prostate cancer cell migration. Because disassembly of adhesion complexes through...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (10): 2161–2173.
Published: 15 May 2014
... of cancers including osteosarcoma, glioma, melanoma, pancreatic and prostate cancer, as well as in tumour vasculature ( Ishiwata et al., 2011a ; Krupkova Jr et al., 2010 ). Much evidence of the function of nestin in cancer is correlative, suggesting that nestin expression might have prognostic value...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (20): 4800–4811.
Published: 15 October 2012
...Zhipeng Zou; Fangyin Zeng; Wanfu Xu; Chunxia Wang; Zhiyong Ke; Q. Jane Wang; Fan Deng Summary Although protein kinase D3 (PKD3) has been shown to contribute to prostate cancer cell growth and survival, the role of PKD in prostate cancer cell motility remains unclear. Here, we show that PKD2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (5): 1204–1216.
Published: 1 March 2012
... A has been shown to be overexpressed in 96% of high-grade prostate intraepithelial neoplasia (PIN) and 98% of prostate cancer lesions ( Lee et al., 2006 ). Aurora A ablation in PC3 cells suppresses cell growth, induces apoptosis, attenuates cell migration and inhibits the growth of human prostate cancer...
Journal Articles
J Cell Sci (2010) 123 (10): 1663–1673.
Published: 15 May 2010
... adhesions. We now report that DU145 human prostate cancer cells with reduced levels of PAK4 expression are unable to successfully migrate in response to HGF, have prominent actin stress fibres, and an increase in the size and number of focal adhesions. Moreover, these cells have a concomitant reduction...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (7): 957–968.
Published: 1 April 2008
... that pathological mutations within the NLS of AR that are associated with prostate cancer and androgen-insensitivity syndrome reduce the binding affinity to importin-α and, subsequently, retard nuclear import; surprisingly, however, the transcriptional activity of these mutants varies widely. Thus, in addition...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (18): 4187–4198.
Published: 15 September 2005
...Pascal Farla; Remko Hersmus; Jan Trapman; Adriaan B. Houtsmuller The androgen receptor (AR) is essential for development of the male gender and in the growth of the majority of prostate cancers. Agonists as well as most antagonists induce translocation of the receptor to the nucleus, whereas only...
Journal Articles
J Cell Sci (2004) 117 (18): 4135–4142.
Published: 15 August 2004
... to this work 19 4 2004 © The Company of Biologists Limited 2004 2004 Prostate cancer Translocon Puromycin Calcium leak Endoplasmic reticulum LNCaP cells The endoplasmic reticulum (ER) plays an essential role in the folding and maturation of proteins and is also the largest...
Journal Articles
J Cell Sci (2002) 115 (1): 141–151.
Published: 1 January 2002
... Prostate cancer © The Company of Biologists Limited 2002 2002 2 10 2001 *Author for correspondence (e-mail: budunovai@amc.org ) References Baldwin, A. S., Jr ( 1996 ). The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol . 14 , 649 -683...