... RNAi or overexpression of Peroxin genes in Drosophila fat body or cells revealed peroxisome independent roles in lipid storage, with Pex14 causing the strongest phenotypes. Drosophila Lipid droplets Perilipins Peroxins Natural Sciences and Engineering Research Council of Canada...

... or neutral lipid core of LDs impact their metabolism and function, the proteome of LDs has emerged as a major influencer in all aspects of LD biology. The perilipins (PLINs) are the most studied and abundant proteins residing on the LD surface. This Cell Science at a Glance and the accompanying poster...

... a specific set of proteins. Most of these proteins associate with LDs through either an amphipathic helix or a membrane-embedded hairpin motif. Here, we address the question of whether integral membrane proteins can localize to the surface of LDs. To test this, we fused perilipin 3 (PLIN3), a mammalian LD...

...-Mackie , E. J. , Dwyer , N. K. , Barber , T. , Coxey , R. A. , Takeda , T. , Rondinone , C. M. , Theodorakis , J. L. , Greenberg , A. S. and Londos , C. ( 1995 ). Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes . J. Lipid Res...