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Keywords: PAK
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Journal Articles
J Cell Sci (2019) 132 (10): jcs217869.
Published: 21 May 2019
... important and complex these regulations can be during epithelial morphogenesis. This complexity is mirrored by the fact that Cdc42 can exert its function through many effector proteins. In epithelial cells, these include atypical PKC (aPKC, also known as PKC-3), the P21-activated kinase (PAK) family...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (10): 1663–1673.
Published: 15 May 2010
... J. R. W. , Jones G. E. , Wells C. M. ( 2008 ). A PAK4-LIMK1 pathway drives prostate cancer cell migration downstream of HGF . Cell. Signal. 20 , 1320 - 1328 . Arias-Romero L. E. , Chernoff J. ( 2008 ). A tale of two Paks . Biol. Cell 100 , 97 - 108...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2008) 121 (17): 2805–2813.
Published: 1 September 2008
... was mediated in part by Pak. Elucidation of this novel pathway for regulation of the fascin/PKCγ complex in migrating carcinoma cells suggests novel targets for therapeutic intervention in metastasis. * Authors for correspondence (e-mail: adamsj@ccf.org ; maddy.parsons@kcl.ac.uk ) 13 5 2008...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (7): 989–1001.
Published: 1 April 2008
... that control the signaling events mediating the crucial lumen formation step in vascular morphogenesis. * Author for correspondence (e-mail: davisgeo@health.missouri.edu ) 21 12 2007 © The Company of Biologists Limited 2008 2008 EC lumen formation Rho GTPases Pak Polarity PKC...
Journal Articles
J Cell Sci (2008) 121 (7): 933–938.
Published: 1 April 2008
... Ciencias Naturales, CSIC, 28006 Madrid, Spain 14 1 2008 © The Company of Biologists Limited 2008 2008 Rac small GTPase E-cadherin PAK Cell-cell adhesion Keratinocytes E-cadherin is one of the most important cell-cell adhesion receptors involved in tissue morphogenesis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (17): 3583–3592.
Published: 1 September 2006
... ). Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (γ-PAK). J. Muscle Res. Cell Motil. 19 , 839 -854. Devreotes, P. and Janetopoulos, C. ( 2003 ). Eukaryotic chemotaxix: distinctions between directional sensing and polarization. J. Biol. Chem. 278 , 20445 -20448...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2001) 114 (11): 1973–1980.
Published: 1 June 2001
... for correspondence (e-mail: davie@hms.harvard.edu ) © The Company of Biologists Limited 2001 2001 GTPase Rho family Actin Rac Pak Dock Kalirin The development of the embryonic nervous system requires that nascent axons extend across a complex extracellular terrain in order to reach...
Journal Articles
J Cell Sci (2000) 113 (3): 471–482.
Published: 1 February 2000
...Qi Zeng; David Lagunoff; Ruthann Masaracchia; Zoe Goeckeler; Graham Côté; Robert Wysolmerski ABSTRACT The p21-activated kinase (PAK) family includes several enzyme isoforms regulated by the GTPases Rac1 and Cdc42. PAK1, found in brain, muscle and spleen, has been implicated in triggering...
Journal Articles
J Cell Sci (1998) 111 (16): 2433–2443.
Published: 15 August 1998
... by Company of Biologists 1998 Actin Rac Cortactin PAK Membrane ruffling The actin cytoskeleton plays an important role in numerous cellular processes, including motility, cytokinesis and cell shape ( Bretscher, 1991 ; Condeelis, 1993 ). Mammalian cells exhibit two major types of actin...