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Journal: Journal of Cell Science
J Cell Sci (2012) 125 (2): 376–386.
Published: 15 January 2012
... underlying this effect. We find that stress-induced senescence induces decreased fibroblast Tiam1 protein levels and increased osteopontin levels, and that senescent fibroblast lysates induce Tiam1 protein degradation in a calcium- and calpain-dependent fashion. Changes in fibroblast Tiam1 protein levels...
Includes: Supplementary data