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Keywords: Oscillations
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Journal Articles
J Cell Sci (2013) 126 (20): 4614–4626.
Published: 15 October 2013
... Dictyostelium , secreted cAMP serves as a chemoattractant, with extracellular cAMP propagated as oscillating waves to ensure directional migratory signals. cAMP oscillations derive from transient excitatory responses of adenylyl cyclase, which then rapidly adapts. We have studied chemotactic signaling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (9): 1492–1502.
Published: 1 May 2010
... by phospholipase C (PLC)-activating receptor agonists or stimulatory glucose concentrations was paralleled by increased PtdIns(4) P levels. In addition, glucose-stimulated cells regularly showed anti-synchronous oscillations of the two lipids. Whereas glucose-induced PtdIns(4) P elevation required voltage-gated Ca...
Includes: Supplementary data