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Keywords: Nuclear translocation
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Journal Articles
Journal Articles
J Cell Sci (2021) 134 (15): jcs252981.
Published: 3 August 2021
... of Biologists Ltd 2021 Summary: This Review expands our knowledge and contributes to research focusing on the role of TFEB in host-pathogen relationships and the feasibility of TFEB as a drug target. Autophagy Lysosome Inflammatory TFEB Nuclear translocation Infection Innate immunity...
Journal Articles
J Cell Sci (2021) 134 (8): jcs255273.
Published: 22 April 2021
... through the P62-NRF2 axis. We supposed that NRP1 inhibits P62 and then the nuclear translocation of NRF2, which leads to the decrease of AKR1B10 expression. However, the additional mechanisms need to be explored. NRP1 has been reported to be involved in a previously undiscovered endocytic pathway...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (18): jcs229534.
Published: 26 September 2019
... that the p38 dissociated from mutant K8 makes a complex with Hsp70, which is known as a potential chaperone for p38 nuclear translocation. Comparison of p38 MAPK binding with keratin variants associated with liver disease showed that the K18 I150V variant dramatically reduced binding with p38, which is similar...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (22): jcs219782.
Published: 19 November 2018
... exportin 1 (CRM1)-dependent pathway. 2-Oxoglutarate 2-OG Dioxygenase inhibitors FIH Factor inhibiting HIF HIF asparaginyl hydroxylase Hypoxia Nuclear translocation As solid tumours grow and oxygen becomes limiting, hypoxia triggers cellular and physiological events ( Ratcliffe, 2013...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2015) 128 (3): 487–498.
Published: 1 February 2015
... formation, which correlated with reduced Smad2 nuclear translocation. Interestingly, we also detected an increase in p38 MAPK phosphorylation and apoptosis in aPKC-silenced cells, which were found to be TRAF6-dependent. Taken together, our results suggest that aPKC isoforms regulate Smad and non-Smad TGFβ...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2013) 126 (2): 625–637.
Published: 15 January 2013
...@faculty.chiba-u.jp ) 13 11 2012 © 2013. Published by The Company of Biologists Ltd 2013 ErbB4 Nuclear translocation EGFR Src-family tyrosine kinases Histone modification Protein-tyrosine kinases are found in multicellular organisms and have important roles in a variety...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (14): 3421–3429.
Published: 15 July 2012
... cells transfected with p35 G2A–Cdk5 or p39 G2A–Cdk5, compared with those expressing p35–knCdk5 or p39-knCdk5 or control mock transfected cells (data not shown). We suggested in Fig. 3 that phosphorylation at Thr84 regulates nuclear translocation of p39. To illustrate this more clearly, we...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (10): 1716–1723.
Published: 15 May 2010
... regulatory mechanism of EGFR nuclear function and could have important implications for evaluating nuclear localization in cancer. * Author for correspondence ( jschroeder@azcc.arizona.edu ) 6 3 2010 © 2010. 2010 MUC1 EGFR Cyclin D1 Nuclear translocation Breast cancer...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (8): 1604–1611.
Published: 15 April 2006
.... Following Ca 2+ -calmodulin stimulation, calcineurin dephosphorylates NFAT proteins and induces their translocation into the nucleus. However, NFAT nuclear translocation has never been investigated in skeletal muscle in vivo. To determine whether NFATc1 nucleocytoplasmic shuttling depends on muscle activity...
Journal Articles
J Cell Sci (2002) 115 (10): 2165–2177.
Published: 15 May 2002
... our understanding of iron-induced damage of nuclear constituents. * Authors for correspondence (e-mail: jrc3@psu.edu , mfried@psu.edu and kjm13@psu.edu ) 26 2 2002 © The Company of Biologists Limited 2002 2002 Iron Oxidative damage DNA protection Nuclear translocation...
Journal Articles
J Cell Sci (2001) 114 (12): 2327–2334.
Published: 15 June 2001
...-specific nuclear translocation, cultured corneal epithelial cells and corneal fibroblasts were transfected with a series of deletion constructs for the heavy chain of ferritin, ferritin-H, tagged with a human c-myc epitope. The subcellular localization of the ferritin was determined by immunofluorescence...
Journal Articles
J Cell Sci (2000) 113 (17): 3085–3091.
Published: 1 September 2000
... progression. Deregulation of this mechanism may be leukaemogenic. * Author for correspondence (e-mail: gdenis@bu.edu ) 16 06 2000 09 08 2000 © 2000 by Company of Biologists 2000 RING3 Nuclear translocation Immunolocalisation Confocal microscopy Leukaemia RING3...
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1993) 104 (4): 949–955.
Published: 1 April 1993
..., 28 Rue du Docteur Roux, 75015 Paris, France † Author for correspondence © 1992 by Company of Biologists 1992 transcription factors signal transduction nuclear translocation Over the last few years a number of international meetings have boasted titles along the lines...