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Keywords: Nuclear shape
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Journal Articles
J Cell Sci (2022) 135 (13): jcs259692.
Published: 4 July 2022
...Sampada Mishra; Daniel L. Levy ABSTRACT Nuclear shape influences cell migration, gene expression and cell cycle progression, and is altered in disease states like laminopathies and cancer. What factors and forces determine nuclear shape? We find that nuclei assembled in Xenopus egg extracts...
Includes: Supplementary data
Journal Articles
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Lipid Biology
J Cell Sci (2009) 122 (12): 1970–1978.
Published: 15 June 2009
... to disorganization of the peripheral ER and abnormal nuclear shape. These results suggest that lipid metabolism contributes to NE dynamics; however, since yeast undergo closed mitosis, the relevance of these observations to higher eukaryotes is unclear. In mammals, lipin has been implicated in adipose tissue...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (11): 1887–1898.
Published: 1 June 2008
..., by alternative splicing and alternative translation initiation, aberrant Nesprin-2 Giant isoforms that lacked an ABD but that were sufficient to restore nuclear shape and emerin localization; this suggests that other regions of Nesprin-2 Giant, potentially including its spectrin repeats, are crucial...
Includes: Supplementary data