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Keywords: Nuclear envelope
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Journal Articles
Journal Articles
J Cell Sci (2023) 136 (21): jcs261385.
Published: 13 November 2023
...Sarah R. Barger; Lauren Penfield; Shirin Bahmanyar ABSTRACT Barrier-to-autointegration factor (BAF) protein is a DNA-binding protein that crosslinks chromatin to allow mitotic nuclear envelope (NE) assembly. The LAP2-emerin-MAN1 (LEM)-domain protein LEMD2 and ESCRT-II/III hybrid protein CHMP7 close...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2023) 136 (7): jcs260155.
Published: 27 March 2023
...Hanna Thoma; Luisa Grünewald; Silke Braune; Elisabeth Pasch; Manfred Alsheimer ABSTRACT SUN domain proteins are conserved proteins of the nuclear envelope and key components of the LINC complexes (for ‘linkers of the nucleoskeleton and the cytoskeleton’). Previous studies have demonstrated...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2022) 135 (8): jcs259493.
Published: 3 May 2022
.... and Paluch , E. K. ( 2015 ). Force transmission during adhesion-independent migration . Nat. Cell Biol. 17 , 524 - 529 . 10.1038/ncb3134 Berk , J. M. , Tifft , K. E. and Wilson , K. L. ( 2013 ). The nuclear envelope LEM-domain protein emerin . Nucleus 4 , 298 - 314...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2021) 134 (12): jcs258194.
Published: 21 June 2021
...Zeinab Jahed; Nya Domkam; Jessica Ornowski; Ghafar Yerima; Mohammad R. K. Mofrad ABSTRACT Large protein complexes assemble at the nuclear envelope to transmit mechanical signals between the cytoskeleton and nucleoskeleton. These protein complexes are known as the linkers of the nucleoskeleton...
Journal Articles
J Cell Sci (2020) 133 (20): jcs242172.
Published: 30 October 2020
... in interphase and becomes dumbbell shaped during mitotic division to facilitate the transfer of one nucleus to the daughter cell. Because yeast cells undergo closed mitosis, the nuclear envelope remains intact throughout the cell cycle. The pathways that regulate nuclear shape are not well characterized...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (16): jcs246546.
Published: 17 August 2020
... DNA, histones and various other nuclear proteins, including those enriched at the nuclear envelope, BAF appears to be essential for replicating cells to protect the genome and enable cell division. Cellular processes, such as innate immunity, post-mitotic nuclear reformation, repair of interphase...
Journal Articles
J Cell Sci (2020) 133 (6): jcs238527.
Published: 26 March 2020
... in glycosylphosphatidylinositol (GPI), localizes to the nuclear envelope (NE). Although this NE localization is essential for Drosophila development, the underlying molecular mechanism remains unknown. To elucidate this mechanism, we identified PIG-B-interacting proteins by performing immunoprecipitation followed by proteomic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (14): jcs229245.
Published: 15 July 2019
..., the nuclear envelope possesses unique mechanical properties, which enables it to resist cytoskeletal forces. Here, we review studies that are beginning to provide quantitative insights into nuclear membrane mechanics. We discuss how the mechanical properties of the fused nuclear membranes mediate...
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J Cell Sci (2018) 131 (20): jcs218024.
Published: 26 October 2018
..., is synthesized by the PIG enzymes. Most PIGs are localized to the endoplasmic reticulum (ER), but Drosophila PIG-B (DmPIG-B) is localized to the nuclear envelope (NE). To determine whether the NE localization of DmPIG-B is functionally important, we defined the determinants of localization and generated an ER...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (18): jcs217513.
Published: 20 September 2018
... at various stages and stained with Lamin B1 antibody to show the nuclear periphery and, chromatin labeled with DAPI. We found that by late neurula stages (NF stage 18), the nuclear envelope is ruffled and irregular, though the chromatin distribution is still largely ellipsoid ( Fig. 1 F). We note...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (14): jcs203653.
Published: 20 July 2018
... approaches used in comparative biology studies. Chromosome segregation Comparative biology Evolution Mitosis Nuclear envelope Spindle The generality of cell biological mechanisms has become a go-to argument for researchers explaining the relevance of their work to funding bodies...
Journal Articles
J Cell Sci (2017) 130 (10): 1822–1834.
Published: 15 May 2017
.... Summary: There are compositional and structural differences in the nuclear pore complexes present in the functionally differentiated macronucleus and micronucleus within the single cytoplasm of ciliated protozoa. FG-Nup Nuclear dimorphism Nuclear envelope Nucleoporin Y-complex Ciliated...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (2): 444–452.
Published: 15 January 2017
...Marta G. Lete; Richard D. Byrne; Alicia Alonso; Dominic Poccia; Banafshé Larijani ABSTRACT Regulation of nuclear envelope dynamics is an important example of the universal phenomena of membrane fusion. The signalling molecules involved in nuclear membrane fusion might also be conserved during...
Includes: Supplementary data