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Keywords: Myosin Va
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Journal Articles
J Cell Sci (2016) 129 (3): 592–603.
Published: 1 February 2016
..., the molecular basis for this interaction remains poorly defined. Myosin Va (MyoVa or MYO5A) is recruited to WPBs by a Rab27A–MyRIP complex and is thought to be the prime mediator of actin binding, but direct MyRIP–actin interactions can also occur. To evaluate the specific contribution of MyRIP–actin and MyRIP...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (6): 1108–1122.
Published: 15 March 2015
... downstream signaling during long-term potentiation (LTP). However, the identity of the motor protein that mediates the local transfer of recycled TrkB-FL back to the plasma membrane remains unclear. Here, we report that the F-actin-based motor protein myosin Va (Myo5a) mediates the postendocytic recycling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (17): 3111–3122.
Published: 1 September 2007
...Alistair N. Hume; Dmitry S. Ushakov; Abul K. Tarafder; Michael A. Ferenczi; Miguel C. Seabra Melanosome transport in melanocytes is a model system for the study of cytoskeletal regulation of intracellular transport. Melanophilin (Mlph) is a Rab27a- and myosin Va (MyoVa)-binding protein...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2004) 117 (26): 6473–6483.
Published: 15 December 2004
... other expressed proteins, melanophilin and myosin Va, both of which are required for normal melanosome distribution in melanocytes, were not required in RPE, despite the association of myosin Va with the RPE melanosome fraction. Both myosin VIIa and myosin Va were immunodetected broadly in sections...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2004) 117 (19): 4509–4515.
Published: 1 September 2004
...Richard T. Libby; Concepcion Lillo; Junko Kitamoto; David S. Williams; Karen P. Steel Myosin Va is an actin-based motor molecule, one of a large family of unconventional myosins. In humans, mutations in MYO5A cause Griscelli syndrome type 1 and Elejalde syndrome, diseases characterized...
Journal Articles
J Cell Sci (2003) 116 (22): 4639–4650.
Published: 15 November 2003
...) in retrograde movement. Immunofluorescence screening with isoform-specific myosin antibodies reveals colocalization of tetanus toxin-containing retrograde carriers with myosin Va. Motor neurons from homozygous myosin Va null mice showed slower retrograde transport compared with wild-type cells, establishing...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2003) 116 (7): 1339–1348.
Published: 1 April 2003
... we provide morphological and biochemical evidence that myosin Va is associated with secretory granules. Expression of a dominant-negative tail domain of myosin Va in PC12 cells led to an extensive clustering of secretory granules close to the cell periphery, a loss of their cortical restriction...
Includes: Multimedia, Supplementary data