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Keywords: Motility
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Journal Articles
J Cell Sci (2023) 136 (18): jcs260964.
Published: 18 September 2023
... cancer (TNBC) progression, suggesting that targeting ILT4 could be a strategy to combat TNBC. ILT4 Triple negative breast cancer Proliferation Motility Glucose metabolism China Postdoctoral Science Foundation http://dx.doi.org/10.13039/501100002858 2021M700054 Natural...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (17): jcs261270.
Published: 7 September 2023
...Isadonna F. Tengganu; Luisa F. Arias Padilla; Jonathan Munera Lopez; Jun Liu; Peter T. Brown; John M. Murray; Ke Hu ABSTRACT Motility is essential for apicomplexan parasites to infect their hosts. In a three-dimensional (3D) environment, the apicomplexan parasite Toxoplasma gondii moves along...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2023) 136 (11): jcs260655.
Published: 8 June 2023
...Chandra Ramakrishnan; Cécile Fort; Sara Rute Marques; David J. P. Ferguson; Marion Gransagne; Jake Baum; Soraya Chaouch; Elisabeth Mouray; Linda Kohl; Richard J. Wheeler; Robert E. Sinden ABSTRACT Flagella are important for eukaryote cell motility, including in sperm, and are vital for life cycle...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2020) 133 (8): jcs243097.
Published: 24 April 2020
... revealed paralog-specific functions in cell motility ( Bouchet et al., 2016 ), cell division ( Samora et al., 2011 ) and neurons ( Sayas et al., 2019 ), the CLASP paralogs may be functionally redundant in other settings. More work is needed to define the specific roles of different CLASP paralogs...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (2): jcs239855.
Published: 23 January 2020
...Tom Beneke; Katherine Banecki; Sophia Fochler; Eva Gluenz ABSTRACT Motile eukaryotic flagella beat through coordinated activity of dynein motor proteins; however, the mechanisms of dynein coordination and regulation are incompletely understood. The inner dynein arm (IDA) f complex (also known...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2019) 132 (3): jcs222851.
Published: 11 February 2019
... to deplete microtubule-stabilizing Tau in U87 cells, we determined its impact on cytoskeletal coordination during migration. We demonstrated here that the motility of these Tau-knockdown cells (shTau cells) was significantly (36%) lower than that of control cells. The shTau cells displayed a slightly changed...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (14): 2382–2393.
Published: 15 July 2017
...Weifeng Luo; Radoslav Janoštiak; Ondřej Tolde; Larisa M. Ryzhova; Lenka Koudelková; Michal Dibus; Jan Brábek; Steven K. Hanks; Daniel Rosel ABSTRACT The tyrosine kinase Src acts as a key regulator of cell motility by phosphorylating multiple protein substrates that control cytoskeletal and adhesion...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (10): 1730–1739.
Published: 15 May 2017
... by beta(2)-integrin ligation . Cell Motil. Cytoskeleton   3 , 174 - 188 . 10.1002/1097-0169(200011)47:3<174::AID-CM2>3.0.CO;2-N Eisenmann , K. M. , West , R. A. , Hildebrand , D. , Kitchen , S. M. , Peng , J. , Sigler , R. , Zhang , J. , Siminovitch , K...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2016) 129 (6): 1085–1091.
Published: 15 March 2016
... of actin filaments at barbed ends drives motile processes. Here, we discuss the control of polarized filament assembly by various regulators that interact with and compete for barbed ends. Actin assembly Capping protein Filament barbed end Formin Motility Profilin Remodeling of the actin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (4): 683–694.
Published: 15 February 2015
...Tristan W. Fowler; Archana Kamalakar; Nisreen S. Akel; Richard C. Kurten; Larry J. Suva; Dana Gaddy ABSTRACT The process of osteoclastic bone resorption is complex and regulated at multiple levels. The role of osteoclast (OCL) fusion and motility in bone resorption are unclear, with the movement...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (8): 1672–1683.
Published: 15 April 2014
... ). Biochemistry and biomechanics of cell motility.   Annu. Rev. Biomed. Eng.   7 , 105 – 150 . 10.1146/annurev.bioeng.7.060804.100340 Lohela   M. , Bry   M. , Tammela   T. , Alitalo   K. ( 2009 ). VEGFs and receptors involved in angiogenesis versus lymphangiogenesis.   Curr. Opin. Cell Biol...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (20): 4602–4613.
Published: 15 October 2013
...David M. Graham; Ling Huang; Kenneth R. Robinson; Mark A. Messerli Summary Ca 2+ has long been known to play an important role in cellular polarity and guidance. We studied the role of Ca 2+ signaling during random and directed cell migration to better understand whether Ca 2+ directs cell motility...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (11): 2381–2391.
Published: 1 June 2013
... characterised, including the extracellular-signal-regulated kinases (ERKs) 1 and 2. In a small interfering RNA (siRNA)-based high-throughput wound healing screen performed in A549 lung carcinoma cells, we identified ERK2 but not ERK1 as a strong mediator of HGF-induced motility. This finding was confirmed...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2013) 126 (1): 221–233.
Published: 1 January 2013
... responding to cAMP. Taken together, these findings suggest that similar components control gradient sensing during FA- and cAMP-mediated motility, but the response of polarized cells is more stable, which ultimately helps maintain their directionality. * Author for correspondence ( c.janetopoulos...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (21): 5015–5025.
Published: 1 November 2012
... progenitors in the postnatal dentate gyrus.   J. Neurosci.   28 , 6720 – 6730 . 10.1523/JNEUROSCI.1677-08.2008 Blaser   H. , Eisenbeiss   S. , Neumann   M. , Reichman–Fried   M. , Thisse   B. , Thisse   C. , Raz   E. ( 2005 ). Transition from non-motile behaviour to directed...
Journal Articles
J Cell Sci (2012) 125 (19): 4475–4486.
Published: 1 October 2012
...-invasive capacities. Thus, we identify LCN2 and TWEAKR-TWEAK as crucial downstream effectors of NFAT1 that regulate breast cancer cell motility and invasive capacity. We also evaluated the mechanisms by which LCN2 modulates breast cancer cell invasion downstream of NFAT1. To this end, we examined...
Includes: Supplementary data