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Keywords: Mitochondrial morphology
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Journal Articles
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Mitochondria
J Cell Sci (2023) 136 (13): jcs260993.
Published: 7 July 2023
... by TOMM20 ) and inner membrane (TIM23, encoded by TIMM23 ) while associating with TOM40 ( TOMM40 ). Intriguingly, this interaction affects mitochondrial morphology, but not protein import or respiratory function; raising the prospect of an intrinsic rescue mechanism. Indeed, Tau P301L induced the formation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (10): jcs260578.
Published: 18 May 2023
... experiment, mitochondrial morphology of at least 100 cells per strain was quantified. For the overexpression strains, also ER morphology of at least 50 cells with altered mitochondrial morphology was analyzed. (F) Overexpression of cqd1(E330A) and CQD2 also leads to the generation of mitochondria–ER...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (14): jcs244632.
Published: 29 July 2020
..., thereby maintaining carrier translocase integrity. Mitochondria TIM22 complex Polytopic protein import Mitochondrial morphology Mitochondrial DNA The predicted topology of Tim22 closely resembles that of Tim23 and Tim17, containing four transmembrane regions (TM1, TM2, TM3 and TM4...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (14): 3153–3161.
Published: 15 July 2005
...-negative activity, yielding normal mitochondrial morphology with an elongated tubular network ( Fig. 2A ; micrographs not shown). This normal mitochondrial morphology in the presence of Mfn2 T130A,ΔTM is noteworthy since it has been shown, as mentioned above, that even a loss-of-function mutant of Mfn2...
Journal Articles
J Cell Sci (2005) 118 (14): 3049–3059.
Published: 15 July 2005
.... Human MTP18 is a novel nuclear-encoded mitochondrial membrane protein, implicated in controlling mitochondrial fission. Upon overexpression of MTP18, mitochondrial morphology was altered from filamentous to punctate structures suggesting excessive mitochondrial fission. Mitochondrial fragmentation...
Journal Articles
J Cell Sci (2001) 114 (19): 3565–3574.
Published: 1 October 2001
... into mitochondria or resulting accumulation of precursor forms of mitochondrial proteins outside the mitochondria are not the causal reason for the aberrant mitochondrial morphology. By contrast, deletion of Mdj1p, a functional partner for mitochondrial Hsp70 in prevention of irreversible protein aggregation...