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Keywords: Mitochondria
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Journal Articles
In collection:
Mitochondria
J Cell Sci (2024) 137 (1): jcs260986.
Published: 10 January 2024
...Claire Caron; Giulia Bertolin ABSTRACT Mitochondria are multifunctional organelles of key importance for cell homeostasis. The outer mitochondrial membrane (OMM) envelops the organelle, and the inner mitochondrial membrane (IMM) is folded into invaginations called cristae. As cristae composition...
Journal Articles
J Cell Sci (2023) 136 (22): jcs261377.
Published: 30 November 2023
... applicability was accessed throughout the Plasmodium liver stage, showing isotropic five-fold expansion. Furthermore, we used PS-ExM to visualise parasite mitochondria as well as the association of lysosomes to the parasitophorous vacuole membrane (PVM) as an example of visualising host–pathogen interaction. We...
Includes: Supplementary data
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In collection:
Mitochondria
J Cell Sci (2023) 136 (22): jcs260790.
Published: 23 November 2023
... by The Company of Biologists Ltd 2023 Summary: A review of the molecular mechanism of MOMP, with a focus on recently discovered roles of BCL-2 proteins in apoptosis and beyond, including what implications these might have in both healthy tissues and disease. BCL2 Apoptosis Mitochondria MOMP BAX...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (17): jcs260857.
Published: 1 September 2023
... Membranes Mitochondria Phosphatidylethanolamine Phospholipids Welch Foundation http://dx.doi.org/10.13039/100000928 A-1810 Texas A&M University http://dx.doi.org/10.13039/100007904 National Institute of General Medical Sciences http://dx.doi.org/10.13039/100000057...
Journal Articles
In collection:
Mitochondria
J Cell Sci (2023) 136 (15): jcs260822.
Published: 31 July 2023
...). This small genome is crucial for the proper functioning of mitochondria, the energy-converting organelles. In mammals, mtDNA is arranged into macromolecular complexes called nucleoids that serve as functional stations for its maintenance and expression. Here, we aimed to explore an uncharacterized protein...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2023) 136 (13): jcs260993.
Published: 7 July 2023
... of tunnelling nanotubes (TNTs), potentially for the recruitment of healthy mitochondria from neighbouring cells and/or the disposal of mitochondria incapacitated by aggregated Tau. Consistent with this, inhibition of TNT formation (and rescue) reveals Tau-induced import impairment. In primary neuronal cultures...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (11): jcs260638.
Published: 6 June 2023
... preserving neuronal energy homeostasis. Here, we review the contribution of mitophagy, a selective form of autophagy that targets dysfunctional or superfluous mitochondria for degradation, in maintaining nervous system homeostasis. In addition, we discuss recent evidence implicating defective or dysregulated...
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Series: REVIEW COMMONS TRANSFER
J Cell Sci (2023) 136 (1): jcs260705.
Published: 12 January 2023
...Leeba Ann Chacko; Felix Mikus; Nicholas Ariotti; Gautam Dey; Vaishnavi Ananthanarayanan ABSTRACT Association with microtubules inhibits the fission of mitochondria in Schizosaccharomyces pombe . Here, we show that this attachment of mitochondria to microtubules is an important cell-intrinsic factor...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (1): jcs260279.
Published: 3 January 2023
... of Biologists Ltd 2023 Summary: Inhibition of mitochondrial respiration decreases the proliferation of yeast cells that are mutant for Cdc28 (the homolog of mammalian Cdk1) by reducing Cdc28 stability through the Hsp90 co-chaperone Cdc37. Mitochondria Cell cycle Signaling Yeast Chaperone...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (23): jcs259748.
Published: 12 December 2022
...Ian G. Ganley; Anne Simonsen ABSTRACT Mitochondria are crucial organelles that play a central role in various cell signaling and metabolic pathways. A healthy mitochondrial population is maintained through a series of quality control pathways and requires a fine-tuned balance between mitochondrial...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (23): jcs259634.
Published: 30 November 2022
... and communication between organelles, providing novel insights into the inner works of a cell. In this Review, with the mitochondria under the spotlight, we discuss the most recent findings on the mechanisms mediating the communication between organelles, focusing on Ca 2+ signaling, lipid exchange, cell death...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (22): jcs259823.
Published: 23 November 2022
.... Mitochondria are optimised for providing energy and buffering Ca 2+ . However, our understanding of the role of mitochondria in regulating synaptic plasticity is incomplete. Here, we have used optical and electrophysiological techniques in cultured hippocampal neurons and ex vivo hippocampal slices from mice...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (21): jcs259980.
Published: 31 October 2022
...Antoineen J. White; Clare S. Harper; Erica M. Rosario; Jonathan V. Dietz; Hannah G. Addis; Jennifer L. Fox; Oleh Khalimonchuk; Laura L. Lackner ABSTRACT Num1 is a multifunctional protein that both tethers mitochondria to the plasma membrane and anchors dynein to the cell cortex during nuclear...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (13): jcs259924.
Published: 8 July 2022
.... The peroxisomal membrane protein PEX11β (also known as PEX11B) and the tail-anchored adaptor proteins FIS1 (mitochondrial fission protein 1) and MFF (mitochondrial fission factor), which recruit the fission GTPase DRP1 (dynamin-related protein 1, also known as DNML1) to both peroxisomes and mitochondria, are key...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (8): jcs258937.
Published: 19 April 2022
.... Most of the miRNAs found inside mitochondria are encoded in the nuclear genome, with a few mitochondrial genome-encoded non-coding RNAs having been reported. In this study, we have identified 13 mitochondrial genome-encoded microRNAs (mitomiRs), which were differentially expressed in breast cancer cell...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (6): jcs259455.
Published: 21 March 2022
... Mitochondria Lysosome Cancer Ca 2+ Mitophagy Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659 VO 376/19-1 BI 484/6-1 GR 4315/2-1 BR 1034/7-1 Ludwig-Maximilians-Universität München http://dx.doi.org/10.13039/501100005722 Liver cancers...
Includes: Supplementary data