1-20 of 208
Keywords: Mitochondria
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (8): jcs258937.
Published: 19 April 2022
.... Most of the miRNAs found inside mitochondria are encoded in the nuclear genome, with a few mitochondrial genome-encoded non-coding RNAs having been reported. In this study, we have identified 13 mitochondrial genome-encoded microRNAs (mitomiRs), which were differentially expressed in breast cancer cell...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (6): jcs259455.
Published: 21 March 2022
... triggers rapid, mitochondria-mediated, non-apoptotic cell death in metastatic melanoma . Cell Reports 37 , 109848 . 10.1016/j.celrep.2021.109848 Duchen , M. R. ( 2000 ). Mitochondria and calcium: from cell signalling to cell death . J. Physiol. 529 , 57 - 68 . 10.1111/j.1469...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (3): jcs248534.
Published: 7 February 2022
... frontotemporal dementia (ALS/FTD). Many of these changes can be linked to alterations in endoplasmic reticulum (ER)–mitochondria signaling, including dysregulation of Ca 2+ signaling, autophagy, lipid metabolism, ATP production, axonal transport, ER stress responses and synaptic dysfunction. ER–mitochondria...
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (1): jcs253591.
Published: 10 January 2022
... contacting mitochondria (arrowheads) was analyzed as indicated in Materials and Methods. Experimental values for 26 ROIs and the corresponding average random values are plotted. A representative experiment out of three is shown. a.u., arbitrary units. (H) Smaug1–EYFP-transfected U2OS cells were live-stained...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (1): jcs259254.
Published: 10 January 2022
...Imadeddin Hijazi; Emily Wang; Michelle Orozco; Sarah Pelton; Amy Chang ABSTRACT Endoplasmic reticulum stress (ERS) occurs when cellular demand for protein folding exceeds the capacity of the organelle. Adaptation and cell survival in response to ERS requires a critical contribution by mitochondria...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2022) 135 (5): jcs259073.
Published: 16 December 2021
..., and dissociates in response to both diacylglycerol and nanomolar elevations of cytosolic Ca 2+ . Loss of TMEM24 results in hyper-accumulation of Ca 2+ in the ER and in excess Ca 2+ entry into mitochondria, with resulting impairment in glucose-stimulated ATP production. References Alford , S. C...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2021) 134 (24): jcs258944.
Published: 15 December 2021
...Rasha Sabouny; Timothy E. Shutt ABSTRACT The dynamic nature of mitochondria, which can fuse, divide and move throughout the cell, allows these critical organelles to adapt their function in response to cellular demands, and is also important for regulating mitochondrial DNA (mtDNA). While...
Journal Articles
J Cell Sci (2021) 134 (22): jcs258653.
Published: 25 November 2021
... for targeting a destabilized cytosolic protein to the mitochondria for degradation. * These authors contributed equally to this work ‡ Author for correspondence ( matsuda-nr@igakuken.or.jp ) Handling Editor: Jennifer Lippincott-Schwartz Competing interests The authors declare no competing...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2021) 134 (22): jcs259188.
Published: 24 November 2021
... al. ( 2018 ). Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities . Cancer Metab 6 , 4 . 10.1186/s40170-018-0177-4 Giampazolias , E. and Tait , S. W. ( 2016 ). Mitochondria...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (5): jcs259091.
Published: 2 November 2021
...Nicolò Ilacqua; Irene Anastasia; Andrea Raimondi; Philippe Lemieux; Thomas Q. de Aguiar Vallim; Katalin Toth; Eugene V. Koonin; Luca Pellegrini ABSTRACT Hepatic lipid homeostasis depends on intracellular pathways that respire fatty acid in peroxisomes and mitochondria, and on systemic pathways...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2021) 134 (20): jcs255299.
Published: 20 October 2021
... the mitochondria and endoplasmic reticulum (ER). We identify VDAC of the pathogenic apicomplexan Toxoplasma gondii and demonstrate its importance for parasite growth. We show that VDAC is involved in protein import and metabolite transfer to mitochondria. Further, depletion of VDAC resulted in significant...
Includes: Supplementary data
Journal Articles
In collection:
Imaging , Mitochondria
J Cell Sci (2021) 134 (13): jcs252197.
Published: 13 July 2021
...: Super-resolution microscopy and density-based cluster analysis illuminate the arrangement of mitochondrial inner membrane proteins, providing insight into the cellular context of these proteins. Mitochondria STORM Nanoscopy Mitochondrial complexes Protein import TIM23 COXIV...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2021) 134 (13): jcs258399.
Published: 9 July 2021
...-11 severely affects balanced respiration, mitochondrial morphology and, ultimately, whole animal physiology. Caenorhabditis elegans Worm Mitochondria Respiration Electron transfer chain Supercomplexes Respirasome Mitochondrial ultrastructure Cryo-electron tomography NDUF-11...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (11): jcs256230.
Published: 7 June 2021
... to amino acid metabolism and mitochondrial fitness. Aging IFN signaling Interferon regulatory factor 7 Cellular metabolism Mitochondria Branched-chain amino acid degradation Competition for food and response to infections are the major challenges for survival and evolution ( Darwin, 1859...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (10): jcs255844.
Published: 20 May 2021
... Miro1 and Miro2 (collectively Miro, also known as RhoT1 and RhoT2, respectively). Here, we investigate which mitochondrial and cellular processes depend on the coordination of Myo19 and microtubule-based motor activities. To this end, we created Myo19-deficient HEK293T cells. Mitochondria in these cells...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (7): jcs226084.
Published: 13 April 2021
...Antonina J. Kruppa; Folma Buss ABSTRACT Mitochondria are multifunctional organelles that not only produce energy for the cell, but are also important for cell signalling, apoptosis and many biosynthetic pathways. In most cell types, they form highly dynamic networks that are constantly remodelled...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (5): jcs253757.
Published: 5 March 2021
... and cellular components, with one feature being their lack of traditional mitochondria, and they have been considered ‘amitochondriate’. These organisms do, however, possess a mitochondrial remnant termed the ‘mitosome’, which retains the biosynthetic machinery for iron-sulfur clusters and some transport...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (4): jcs257162.
Published: 25 February 2021
... resulted in enhanced oxidative respiration and ATP flux. In addition to the presence of ANT proteins in the mitochondria, they reside at the plasma membrane in airway epithelial cells and regulate airway homeostasis. ANT2 overexpression stimulates airway surface hydration by ATP and maintains ciliary...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (4): jcs256255.
Published: 22 February 2021
...Paul J. Wrighton; Arkadi Shwartz; Jin-Mi Heo; Eleanor D. Quenzer; Kyle A. LaBella; J. Wade Harper; Wolfram Goessling ABSTRACT Mitophagy, the selective recycling of mitochondria through autophagy, is a crucial metabolic process induced by cellular stress, and defects are linked to aging, sarcopenia...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2021) 134 (3): jcs253401.
Published: 8 February 2021
...-independent manner. Cyclophilin A Immunophilin p23 Mitochondria Apoptosis Trafficking Cyclophilin A (CyPA) is an abundant protein belonging to the immunophilin (IMM) family. As such, it is characterized by the presence of a signature domain of the family, the peptidyl-prolyl isomerase...