... bilayers, which is drastically decreased in a paracrine-deficient mutant of EN2. We propose that the bidirectional plasma membrane translocation events that occur during homeoprotein secretion and internalization are parts of a common process. Funding This work was supported by the Centre National de...

... in the extracellular space. Here we demonstrate that FGF2 membrane translocation can occur in a folded conformation, i.e. unfolded molecules are not obligatory intermediates in FGF2 secretion. Furthermore, we find that initial sorting into its export pathway requires FGF2 to be folded, because the interaction...

... 2007 © The Company of Biologists Limited 2007 2007 Fibroblast growth factor 2 Membrane translocation Unconventional protein secretion Nonclassical export The majority of extracellular proteins are exported from cells through the classical endoplasmic reticulum (ER)/Golgi...

...-mail: hirai-yohei@frontier.kyoto-u.ac.jp ) 17 4 2007 © The Company of Biologists Limited 2007 2007 Epimorphin Integrin Morphogenesis Membrane translocation t-SNARE Morphogenesis, the orchestration of tissue remodeling with cell proliferation, differentiation and apoptosis...

... release from import receptor sites. Release from receptors sites may be rate-limiting in translocation. * Author for correspondence (e-mail: vincenzo.zara@unile.it ) 7 6 2005 © The Company of Biologists Limited 2005 2005 Citrate carrier Mitochondria Membrane translocation...

...Rafael Backhaus; Christoph Zehe; Sabine Wegehingel; Angelika Kehlenbach; Blanche Schwappach; Walter Nickel Endoplasmic reticulum/Golgi-dependent protein secretion depends on signal peptides that mediate membrane translocation of nascent secretory proteins into the lumen of the endoplasmic reticulum...

.... Philos. Trans. R. Soc. Lond. B. Biol. Sci. 300 , 225 -228. ‡ Author for correspondence (e-mail: walter.nickel@urz.uni-heidelberg.de ) 25 6 2002 © The Company of Biologists Limited 2002 2002 Non-conventional protein secretion Non-classical protein export Membrane...

... Limited 2001 2001 Peroxisomes Microbodies Protein trafficking Membrane translocation Chaperones Peroxisomal protein import has been the subject of fruitful research in the past several years, and as a result many steps in this process have been identified (Hettema et al., 1999 ; Kunau...