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Keywords: Membrane traffic
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Journal Articles
In collection:
Membrane Trafficking
J Cell Sci (2022) 135 (16): jcs260112.
Published: 16 August 2022
... regulate SNARE function. However, it is clear that these PTMs provide cells with an incredible functional plasticity; SNARE PTMs enable cells to respond to an ever-changing extracellular environment through the rerouting of membrane traffic. In this Review, we summarise key findings regarding SNARE...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (7): jcs257311.
Published: 13 April 2021
... binding domain, named RBD11, that can be used for visualizing and temporally analyzing endogenous, active Rab11 in mammalian cultured cells. Rab11 Effector Membrane traffic Rab11-binding domain Small GTPase Rab Trapper Rab GTPases belong to the Ras superfamily of small GTPases and play...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (20): jcs222992.
Published: 21 October 2019
... complex Clathrin Membrane traffic Endocytosis Golgi Hereditary spastic paraplegia Nearly a third of the proteins encoded by the human genome are predicted to be integral membrane proteins, all of which have to get to the right part of the cell. There are several ways of moving membrane...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (15): jcs231159.
Published: 2 August 2019
...Takuro Tojima; Yasuyuki Suda; Midori Ishii; Kazuo Kurokawa; Akihiko Nakano ABSTRACT The trans -Golgi network (TGN) acts as a sorting hub for membrane traffic. It receives newly synthesized and recycled proteins, and sorts and delivers them to specific targets such as the plasma membrane, endosomes...
Includes: Supplementary data
Journal Articles
In collection:
Autophagy
J Cell Sci (2018) 131 (7): jcs215442.
Published: 6 April 2018
.... Autophagy Autolysosome Lysosome Membrane traffic Rab7 For the TEM analysis, cells grown in the complete medium for 2 days were cultured for 2 h in either fresh complete medium or EBSS for 2 h. The cells were then fixed for 30 min at 4°C with 2% paraformaldehyde and 2% glutaraldehyde in 0.1 M...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (24): 4155–4167.
Published: 15 December 2017
.... Anat.   131 , 321 - 332 . Sztul , E. and Lupashin , V. ( 2009 ). Role of vesicle tethering factors in the ER-Golgi membrane traffic . FEBS Lett.   583 , 3770 - 3783 . 10.1016/j.febslet.2009.10.083 Szul , T. and Sztul , E. ( 2011 ). COPII and COPI traffic at the ER...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (14): 2423–2429.
Published: 15 July 2015
... ( Bryant and Gould, 2011 ; Bryant et al., 2002 ). This is disrupted during the insulin-resistance underlying type-2 diabetes. Endosome Gyrin Membrane traffic Summary: Cellugyrin-containing internal GLUT4-containing vesicles provide an insulin-sensitive reservoir to replenish GLUT4...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (12): 2351–2362.
Published: 15 June 2015
... protein Membrane traffic Exocyst BBSome Protein–protein interaction Anti-GFP nanobody Following the complete sequencing of the genomes of humans and other organisms, studies of the interactions between known proteins have improved our understanding of protein function. Protein–protein...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (8): 1595–1606.
Published: 15 April 2015
...   A , Nakayama   K , Yuba-Kubo   A , Katsuno   T , Tsukita   S , Tsukita   S 2007 Functional involvement of TMF/ARA160 in Rab6-dependent retrograde membrane traffic. Exp. Cell Res.   313 3472 3485 10.1016/j.yexcr.2007.07.010 Yang   JS , Lee   SY , Spanò   S , Gad   H...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (20): 4409–4419.
Published: 15 October 2014
... Polarity Neuron Migration Membrane traffic FRAP Neurons are extremely polarized cells, with axons specialized in delivering electrical signals that trigger the release of neurotransmitters from presynaptic contacts, and dendrites specialized in sensing neurotransmitters through specific...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (10): 2500–2508.
Published: 15 May 2012
.... , Nelson   S. B. , Jeong   B. , Turkewitz   A. P. ( 2010 ). Comprehensive analysis reveals dynamic and evolutionary plasticity of Rab GTPases and membrane traffic in Tetrahymena thermophila . PLoS Genet.   6 , e1001155 . Burki   F. , Inagaki   Y. , Bråte   J. , Archibald   J. M...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (9): 2235–2243.
Published: 1 May 2012
... that endogenous Rab35 is actually an essential mediator of neurite outgrowth of PC12 cells. * Author for correspondence ( nori@m.tohoku.ac.jp ) 10 1 2012 © 2012. 2012 Rab35 Centaurin-β2 ACAP2 Arf6 Membrane traffic Neurite outgrowth Rab-type and Arf-type small GTPases...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (5): 1318–1328.
Published: 1 March 2012
... COPI ARF ARF-GEF GBF1 Gartenzwerg Drosophila melanogaster Tracheal system Epithelial tube Membrane traffic The dimensions and shapes of epithelial tubules in many organs, such as vertebrate kidneys, lungs and vascular systems, are precisely controlled to ensure normal organ function...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (16): 2924–2934.
Published: 15 August 2009
..., UK 18 5 2009 © The Company of Biologists Limited 2009 2009 COPII Membrane traffic Secretion Vesicle formation The first step of the mammalian secretory pathway is the export of proteins from the ER (reviewed by Hughes and Stephens, 2008 ). The accumulation...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (20): 3433–3444.
Published: 15 October 2008
... © The Company of Biologists Limited 2008 2008 ENTH Membrane traffic Clathrin Spore development Cytokinesis PtdIns(4,5) P 2 Dictyostelium discoideum Clathrin-mediated endocytosis is a highly conserved process in which specific cargo on the plasma membrane is selected...
Journal Articles
J Cell Sci (2008) 121 (19): 3155–3166.
Published: 1 October 2008
... endocytic pathway might reveal new strategies for the downregulation of ErbB2 in breast cancer. Non-clathrin endocytosis Membrane traffic Receptor tyrosine kinase Receptor downregulation Arf6 Rho-family GTPase HER2 ErbB2 is a member of the ErbB family of receptor tyrosine kinases, which...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (18): 3025–3034.
Published: 15 September 2008
.... Biochim. Biophys. Acta 1744 , 304 -315. Watson, P. and Stephens, D. J. ( 2006 ). Microtubule plus-end loading of p150(Glued) is mediated by EB1 and CLIP-170 but is not required for intracellular membrane traffic in mammalian cells. J. Cell Sci. 119 , 2758 -2767. Watson, P., Townley, A. K...
Includes: Supplementary data
Journal Articles
In collection:
Lipid Biology
J Cell Sci (2008) 121 (11): 1852–1860.
Published: 1 June 2008
... appear to be metabolic organelles involved in membrane traffic. J. Biol. Chem. 279 , 3787 -3792. Liu, P., Bartz, R., Zehmer, J. K., Ying, Y. S., Zhu, M., Serrero, G. and Anderson, R. G. ( 2007 ). Rab-regulated interaction of early endosomes with lipid droplets. Biochim. Biophys. Acta 1773...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (10): 1569–1576.
Published: 15 May 2008
..., some of the key molecular components of cytokinesis have been identified, many of which are proteins that function to control membrane traffic. Here, we review recent advances in this area. Traffic from the trans-Golgi network (TGN) and the secretory pathway to the furrow and/or midbody...
Journal Articles
J Cell Sci (2008) 121 (1): 55–64.
Published: 1 January 2008
... complex from ER membranes owing to GTP hydrolysis by Sar1p. Biophysical modelling Domain formation Membrane traffic Systems biology Protein transport along the secretory pathway is initiated by the formation of small coated vesicles at the endoplasmic reticulum (ER). The core machinery...
Includes: Supplementary data