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Keywords: Mammary gland
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Journal Articles
In collection:
J Cell Sci (2021) 134 (22): jcs258905.
Published: 23 November 2021
... acts coordinately with basement membrane components to trigger mammary cyst formation. Mammary gland Syntaxin4 Epithelial morphogenesis Epimorphin Basement membrane Epithelial–mesenchymal transition Japan Society for the Promotion of Science http://dx.doi.org/10.13039/501100001691...
Includes: Supplementary data
Journal Articles
In collection:
J Cell Sci (2021) 134 (1): jcs248849.
Published: 8 January 2021
...-specific Piezo1 deletion. These findings support a multifaceted system of chemical and mechanical sensing in the mammary gland, and a protective redundancy that ensures continued lactational competence and offspring survival. 12 5 2020 6 11 2020 © 2021. Published by The Company...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (12): jcs242495.
Published: 23 June 2020
... in vivo . The adult mammary gland provides a unique model for investigating physiological or pathological processes such as morphogenesis or epithelial cell dissemination. Here, we establish a new pipeline to study rare cellular events occurring in the mammary gland, by combining orthotopic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (11): 2638–2654.
Published: 1 June 2012
... isolation and culture conditions in Matrigel are compatible with simple epithelial organization, complete apical junctional complexes and fluid-filled lumens, consistent with the in vivo organization of mammary ducts in the mouse ( Pitelka et al., 1973 ) and human mammary glands ( Ozzello, 1971 ; Stirling...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2011) 124 (19): 3247–3253.
Published: 1 October 2011
... family of CLD binding proteins, is hypothesized to regulate CLD production in these cells during differentiation of the mammary gland into a secretory organ. We tested this hypothesis by comparing CLD accumulation in differentiating mammary glands of wild-type and ADPH-deficient mice. ADPH deficiency did...
Journal Articles
J Cell Sci (2010) 123 (19): 3316–3328.
Published: 1 October 2010
... are associated with more ‘poorly differentiated’ tumours and a poor outcome in a cohort of 295 breast cancer patients. Mammary gland Epithelial Cell polarity PKCζ Proliferation Breast cancer Mammary epithelial cells (MECs) form acini when cultured on laminin-rich extracellular matrix (ECM...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (4): 606–618.
Published: 15 February 2010
...Stephanie B. Greene; Preethi H. Gunaratne; Scott M. Hammond; Jeffrey M. Rosen In an effort to understand the potential role of microRNAs (miRNAs) in mammary-gland stem or progenitor cells, miRNA microarrays were performed on subpopulations of the mouse mammary epithelial cell (MEC) line COMMA-DβGeo...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (3): 468–477.
Published: 1 February 2007
..., W., Longley, M. A., Roop, D. R., Li, Y. and Rosen, J. M. ( 2006 ). Keratin 6, is not essential for mammary gland development. Breast Cancer Res. 8 , R29 . Hall, E. J. ( 2000 ). Radiobiology for the Radiologist . Philadelphia: Lippincott Williams & Wilkins. He, B., Barg, R. N., You...
Journal Articles
J Cell Sci (2004) 117 (21): 5155–5164.
Published: 1 October 2004
...Mustapha Lkhider; Roberta Castino; Edwige Bouguyon; Ciro Isidoro; Michèle Ollivier-Bousquet The 16 kDa prolactin fragment arises from partial proteolysis of the native 23 kDa prolactin pituitary hormone. The mammary gland has been involved in this processing, although it has not been clarified...
Journal Articles
J Cell Sci (2003) 116 (6): 1137–1149.
Published: 15 March 2003
...Stacey B. Tepera; Pierre D. McCrea; Jeffrey M. Rosen The Wnt (wingless) family of secreted glycoproteins initiates a signalling pathway implicated in the regulation of both normal mouse mammary gland development and tumorigenesis. Multiple Wnt signals ultimately converge on the multifunctional...
Journal Articles
J Cell Sci (2003) 116 (4): 675–682.
Published: 15 February 2003
...-binding proteins (IGFBPs),there is currently no experimental evidence that IGFBPs regulate the survival function of IGFs in the mammary gland. We have examined IGFBP expression during mammary gland development and studied the effects of IGFBPs on IGF-mediated survival and signalling in mammary epithelial...
Journal Articles
J Cell Sci (2002) 115 (23): 4419–4431.
Published: 1 December 2002
... inhibitor BB94,indicating that this morphogenetic process is likely to require MMP activity. Collectively, our results provide evidence that RA promotes lumen formation by mammary epithelial cells in vitro and suggest that it plays a similar role during mammary gland development in vivo. * Author...
Journal Articles
J Cell Sci (2002) 115 (1): 25–37.
Published: 1 January 2002
... gland. To investigate its role in the biology of the mammary gland, we have established transgenic mice bearing the EphB4 receptor under the control of the MMTV-LTR promoter, which represents the first transgenic mouse model to investigate the effect(s) of unscheduled expression of EphB4 in adult...
Journal Articles
J Cell Sci (1988) 1988 (Supplement_10): 95–114.
Published: 1 February 1988
... and human mammary glands. In neoplastic disease the benign, carcinogen-induced rat and benign, human mammary tumours can contain epithelial, myoepithelial-like and alveolar-like cells, whereas their malignant counterparts mainly contain only epithelial-like cells. Clonal epithelial cell lines from normal...