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Keywords: Laminopathies
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Journal Articles
J Cell Sci (2011) 124 (12): 2077–2085.
Published: 15 June 2011
...@neurochem.su.se ) 22 2 2011 © 2011. 2011 Cancer Centrosome Laminopathies Nuclear membrane Nuclear migration The nuclear envelope (NE) separates the nucleoplasm from the cytoplasm and consists of two concentric lipid membranes: the nuclear pores and the nuclear lamina ( Hetzer et al...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (11): 1887–1898.
Published: 1 June 2008
... tissues. Nuclei of primary dermal knockout fibroblasts and keratinocytes were heavily misshapen, displaying a striking similarity to nuclear deformations characteristic of laminopathies. Furthermore, emerin, the protein involved in the X-linked form of Emery-Dreifuss muscular dystrophy (EDMD...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (13): 2704–2714.
Published: 1 July 2006
...Kaliyaperumal Manju; Bhattiprolu Muralikrishna; Veena K Parnaik A-type lamins are components of the nuclear lamina. Mutations in the gene encoding lamin A are associated with a range of highly degenerative diseases termed laminopathies. To evaluate sensitivity to DNA damage, GFP-tagged lamin...